EPA (Eicosapentaenoic Acid)

Insulin

Basophils (Absolute)

Homocysteine

MCH (Mean Corpuscular Hemoglobin)

MCHC (Mean Corpuscular Hemoglobin Concentration)

Copper Serum

MCV (Mean Corpuscular Volume)

Bilirubin (Total and Direct)

Potassium

RDW (Red Cell Distribution Width)

Lipoprotein(a) [Lp(a)]

Tg Ab (Thyroglobulin Antibodies)

A/G Ratio (Albumin/Globulin Ratio)

Lymphocytes (Absolute)

Serum Iron

TNF-α (Tumor Necrosis Factor-alpha)

Ceruloplasmin

Fibrinogen

Monocytes (Absolute)

Neutrophils (Absolute)

SHBG (Sex Hormone Binding Globulin)

Bicarbonate

eGFR (Estimated Glomerular Filtration Rate)

TIBC (Total Iron Binding Capacity)

BUN/Creatinine Ratio

25(OH)D (25-Hydroxyvitamin D)

Platelet Count

Lactic Acid

ApoA/ApoB Ratio

Phosphorous

HS-CRP (High-Sensitivity C-Reactive Protein)

TSH (Thyroid Stimulating Hormone)

Uric Acid

AST (Aspartate Aminotransferase)

HOMA-IR (Homeostatic Model Assessment of Insulin Resistance)

ALT (Alanine Aminotransferase)

Fasting Insulin

NRBC (Nucleated Red Blood Cells)

Immature Granulocytes

ANA, or Antinuclear Antibody, is a crucial biomarker used in assessing the potential risk for autoimmune diseases and overall immune system health for longevity.

ANA (Antinuclear Antibody)

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Biomarker Explained

Biomarkers are crucial indicators of biological processes that can be used to assess an individual’s health and predict their likelihood of developing age-related diseases. In the context of longevity, biomarkers play a vital role in evaluating the effectiveness of interventions aimed at promoting healthy aging and extending lifespan. The interpretation of biomarkers for longevity purposes involves a comprehensive understanding of factors that contribute to aging and age-related diseases. Biomarkers commonly used for assessing longevity include indicators of inflammation, oxidative stress, insulin resistance, and metabolic function. By analyzing these biomarkers, researchers and healthcare professionals can gain insight into an individual’s biological age, as opposed to their chronological age, and identify potential areas for intervention to promote healthy aging. To interpret biomarkers effectively, it is essential to compare the results to established reference ranges and consider them in the context of the individual’s overall health and lifestyle factors. Additionally, longitudinal tracking of biomarker levels over time can provide valuable information about the effectiveness of interventions and the trajectory of aging. In summary, the interpretation of biomarkers for longevity purposes involves a deep understanding of the underlying mechanisms of aging and age-related diseases, as well as the careful analysis of biomarker levels in the context of an individual’s health and lifestyle. This approach allows for the identification of potential areas for intervention and the monitoring of progress towards achieving healthy aging and extended lifespan.

Keywords:

biomarker, longevity, aging, age-related diseases, inflammation, oxidative stress, insulin resistance, metabolic function

How does Rapaymcin work?

Rapamycin slows aging by targeting the mTOR pathway, shifting the body’s focus from growth to repair. It promotes cellular recycling, reduces overgrowth linked to disease, and enhances resilience to stress.

Imagine your body as a city, bustling with activity.

Cells are the workers, and mTOR (mechanistic target of rapamycin) is the city planner, deciding where to focus resources – building new structures, cleaning up waste, or repairing old ones.

As we age, mTOR often prioritizes building (cell growth) over maintenance (cellular repair), leading to “clutter” in our bodies that contributes to aging and disease.

This is where Rapamycin comes in.

It acts like a wise advisor to mTOR, convincing it to slow down unnecessary growth projects and focus on clean up and repair instead.

Specifically, Rapamycin:

Activates cellular recycling (autophagy):

Think of autophagy as the city’s waste management system. Damaged parts of cells are broken down and reused, keeping the system efficient and healthy.

Reduces harmful overgrowth:

Overactive mTOR has been linked to diseases such as cancer, cardiovascular disease, and neurodegenerative conditions like Alzheimer’s. By dialing back excessive growth signals, Rapamycin helps prevent these issues.

Supports stress resilience:

When cells are less focused on growing, they’re better equipped to handle stress, repair damage, and maintain long-term health.