Creatinine

A/G Ratio (Albumin/Globulin Ratio)

Apolipoprotein B

Chloride

Total Testosterone

IL-6 (Interleukin-6)

DHEA-S (Dehydroepiandrosterone Sulfate)

TPO Ab (Thyroid Peroxidase Antibodies)

Copper Serum

Immature Granulocytes

ALT (Alanine Aminotransferase)

Neutrophils (Absolute)

LDL Particle Number

Ferritin

SHBG (Sex Hormone Binding Globulin)

Total Protein

Potassium

Uric Acid

Apolipoprotein A1

Hemoglobin

EPA (Eicosapentaenoic Acid)

RBC Magnesium

GGT (Gamma-Glutamyl Transferase)

Insulin

BUN/Creatinine Ratio

Hematocrit

RBC (Red Blood Cell Count)

Glucose

Lipoprotein(a) [Lp(a)]

Phosphorous

Vitamin A (Retinol)

Reverse T3 (rT3)

VLDL Cholesterol (calculated)

Alkaline Phosphatase (ALP)

Total Cholesterol

WBC (White Blood Cell Count)

DHA (Docosahexaenoic Acid)

BUN (Blood Urea Nitrogen)

Bilirubin (Total and Direct)

Tg Ab (Thyroglobulin Antibodies)

Discover the significance of BUN/Creatinine Ratio as a potential biomarker for assessing longevity and overall health. Learn more about its implications.

BUN/Creatinine Ratio

BUN/Creatinine Ratio is a biomarker that is often used in longevity research to assess kidney function and overall health. The ratio of blood urea nitrogen (BUN) to creatinine levels can provide valuable insights into the body’s ability to eliminate waste products and maintain proper hydration. An elevated BUN/Creatinine Ratio may indicate potential kidney dysfunction or dehydration, which can have implications for long-term health and longevity. By monitoring and optimizing this biomarker, individuals can take proactive steps to support their kidney health and overall well-being as they age.

Biomarker Explained

The BUN/Creatinine Ratio is a valuable biomarker used in longevity research to assess kidney function and overall health. This ratio is calculated by dividing the blood urea nitrogen (BUN) levels by the creatinine levels. A higher BUN/Creatinine Ratio may indicate potential kidney dysfunction or dehydration. The kidneys play a crucial role in filtering waste products from the blood and maintaining proper hydration. Therefore, an elevated ratio suggests that the body may not be effectively eliminating waste products or may be experiencing insufficient fluid intake. For individuals focused on optimizing their longevity, it is important to monitor and optimize this biomarker. Regular testing of the BUN/Creatinine Ratio can provide valuable insights into kidney health and overall well-being. By identifying and addressing potential issues early on, individuals can take proactive steps to support their kidney function and overall health as they age. In conclusion, the BUN/Creatinine Ratio is an important biomarker that provides valuable information about kidney function and hydration levels. By understanding and interpreting this ratio, individuals can take proactive measures to support their longevity and overall well-being.

Keywords:

BUN, Creatinine, Ratio, Biomarker, Longevity, Kidney function, Dehydration

How does Rapaymcin work?

Rapamycin slows aging by targeting the mTOR pathway, shifting the body’s focus from growth to repair. It promotes cellular recycling, reduces overgrowth linked to disease, and enhances resilience to stress.

Imagine your body as a city, bustling with activity.

Cells are the workers, and mTOR (mechanistic target of rapamycin) is the city planner, deciding where to focus resources – building new structures, cleaning up waste, or repairing old ones.

As we age, mTOR often prioritizes building (cell growth) over maintenance (cellular repair), leading to “clutter” in our bodies that contributes to aging and disease.

This is where Rapamycin comes in.

It acts like a wise advisor to mTOR, convincing it to slow down unnecessary growth projects and focus on clean up and repair instead.

Specifically, Rapamycin:

Activates cellular recycling (autophagy):

Think of autophagy as the city’s waste management system. Damaged parts of cells are broken down and reused, keeping the system efficient and healthy.

Reduces harmful overgrowth:

Overactive mTOR has been linked to diseases such as cancer, cardiovascular disease, and neurodegenerative conditions like Alzheimer’s. By dialing back excessive growth signals, Rapamycin helps prevent these issues.

Supports stress resilience:

When cells are less focused on growing, they’re better equipped to handle stress, repair damage, and maintain long-term health.