Physician-Supervised GLP-1 at Full Therapeutic Dose

The results you've seen in others.Precision GLP-1 treatments are here.

A full-dose GLP-1 program, physician-prescribed and monitored from day one.

  • An average of 15 lbs in the first 12 weeks*
  • 92% report sustained results at six months*
  • 50+ biomarkers tracked throughout
  • Physician-managed titration from week one
$179
First month, then $299/mo
Cancel anytime
GLP-1 physician-supervised protocol

AS FEATURED IN

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The power of GLP-1 Medication

0lbs

Average weight lost in the first 12 weeks on physician-supervised GLP-1.*

0%

Of patients report sustained weight loss at six months.*

*Based on patient-reported outcomes.

Unlock your results

Adjust your height and weight below to see your personalized results

Activity
Diet
5' 4"
170 lbs

Estimated weight loss:

-17lbs

Est. GLP-1 Loss

10%

Diabetes Risk

2.6x

Cardiac Risk

1.6x

Sleep Apnea Risk

2.0x

Over-weight

Your BMI is 29.2, which is higher than 38% of the population.

Population
38%
15
20
25
30
35
40
45
BMI

This calculator is for informational purposes only and does not constitute medical advice. Weight loss estimates are based on typical GLP-1 clinical trial results for your BMI category. Risk estimates are derived from large-scale population studies, and the BMI distribution curve is modeled on U.S. adult data. Consult with a healthcare professional for personalized guidance.

GLP-1 medication
0lbs

average weight lost in 12 weeks

0%

report sustained weight loss at 6 months

*Based on patient-reported outcomes.

The #1 GLP-1 Protocol

At therapeutic doses, GLP-1 drives significant fat reduction, improves insulin sensitivity, and reduces chronic inflammation. Your physician monitors your full metabolic picture to ensure you're losing weight safely.

Real, Sustained Weight Loss

Therapeutic-dose GLP-1 reduces appetite, increases satiety, and shifts body composition toward fat loss. Most patients see measurable changes within the first month, with sustained results tracked through quarterly labs.

Energy That Lasts

Improved insulin sensitivity and steadier blood glucose translate to consistent energy throughout the day. Most patients notice the change within two to four weeks.

Metabolic Health Protection

Weight loss at this rate needs monitoring. Your physician tracks 50+ biomarkers including hsCRP, fasting insulin, and inflammatory markers to ensure your metabolic health improves alongside your weight.

Dosing Built Around You

Your physician adjusts your titration schedule based on your response and labs, not a default calendar. This minimizes side effects while keeping you on the most effective dose.

HSA/FSA Eligible
Modify or cancel anytime
Longevity lab panels
Expert guidance
$179/mo
4.9
|10,000+ PATIENTS SERVED

From first assessment to optimized protocol, entirely online

A physician-supervised protocol built around your data, entirely online.

Complete your health assessment
Step 1

Complete your health assessment

A brief intake covering your health history, goals, and current medications.

Five layers of care
all included from $179/month

Your plan combines physician-prescribed medication, CLIA-certified lab testing, the blēo wearable device, AI coaching, and ongoing physician oversight in one protocol.

GLP-1 Medication
GLP-1 Medication

GLP-1 Medication

Physician-prescribed compounded semaglutide or tirzepatide at therapeutic doses.

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Join 500+ patients

The #1 GLP-1 Protocol

  • Physician-prescribed semaglutide or tirzepatide
  • Quarterly lab reviews and dosing optimization
  • bleo wearable and longevity AI included
  • Cancel anytime, no commitment
Doctor Prescribed
Labs Included
Wearable Included
Free Shipping
Licensed US physicians
FDA-regulated medications
100% online
Personalized treatment
Lab tests
Free wearable
Ongoing support
Free shipping
Licensed US physicians
FDA-regulated medications
100% online
Personalized treatment
Lab tests
Free wearable
Ongoing support
Free shipping
Licensed US physicians
FDA-regulated medications
100% online
Personalized treatment
Lab tests
Free wearable
Ongoing support
Free shipping

The results your friends are getting.

GLP-1 Medication

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More than medication

A complete program that keeps your physician in the picture throughout.

Comprehensive metabolic care: physician, medication, and monitoring
Certified physicians
Complete plan
24/7 access to our Care Team
100% online
Dosage and protocol adjustments, as needed
Continuous longevity monitoring
Personal nutrition and lifestyle coaching

Reviews

5/5
312 Reviews
Andrea V.

Quoted $1,200/mo at a clinic, found this for $179

The weight loss clinic near me wanted $1,200 a month and that was just for the medication. No labs, no wearable, no physician follow-up. I started here at $179 for the first month with everything included. Same class of drug, ten times the support.

Robert K.

Lost 40 lbs twice before, gained it back both times

I have lost and regained 40 pounds twice in my life. This time is different because there is a physician watching my metabolic markers and adjusting the protocol. Five months in, 32 lbs down, and I am not relying on willpower alone to keep it off.

Jasmine T.

My physician titrated at a pace I could handle

I was dreading the nausea everyone talks about online. My physician started me lower than the standard protocol and moved up in small steps over six weeks. I had one queasy morning the entire time. Now I am down 19 lbs and never had to take a sick day.

Frequently askedquestions aboutGLP-1 Medication

What brought you here today?

Important Safety Information

GLP-1 medications are FDA-approved under certain brand indications. Compounded versions are not FDA-approved.

Prescription products are subject to healthcare provider approval following an online consultation.

Common side effects may include nausea, vomiting, diarrhea, and constipation, particularly during dose escalation.

Do not take GLP-1 therapies if you have a personal or family history of medullary thyroid carcinoma or MEN 2. Seek urgent care for severe abdominal pain or signs of allergic reaction.

Results vary by person and protocol. Compounded medications are not FDA-approved and are prepared by a licensed pharmacy based on a provider's prescription.

Longevity Direct

The #1 GLP-1 Program

Physician-supervised protocols with labs, tracking, and ongoing support

LegitScript Certification

© 2026 Longr Holdings Inc.

142 West 57th Street | New York, NY 10019

Prescription products require an online consultation with a physician who will determine if a prescription is appropriate. See product page for important safety information. Benefits outlined on Longevity Direct are based on 3rd party studies.

Medical statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. If you are in need of emergency medical attention, please call 911 immediately.