Physician-prescribed GLP-1 Microdose

Light up your best years.Energy, clarity, and weight. Sorted.

A lower-dose GLP-1 protocol prescribed by a US physician.
What patients notice within the first few weeks:

  • Steady energy from morning to evening
  • Gradual, sustainable weight changes without muscle loss
  • Measured reductions in chronic inflammation
  • Fewer side effects than standard GLP-1 dosing
$179/mo
Best price guarantee
Cancel anytime
GLP-1 Microdose wellness protocol

AS FEATURED IN

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A physician reviewed my results personally. For the first time, I felt like someone was paying attention.Lauren M.

4.9/5
500+ patients

The power of GLP-1 Microdose

0/10

Patients report improved sense of wellbeing on GLP-1 protocols.*

0%

Report more consistent energy throughout the day.*

*Based on patient-reported outcomes.

Is a GLP-1 Microdose right for me?

This protocol is designed for people who want real metabolic support, not crash-diet results, with a physician who reviews their lab data.

Selected: Lose stubborn weight without muscle loss

Patient maintaining strength while losing weight

I've lost about 14 pounds over four months. At the same time I've been able to increase my muscle mass. I didn't expect to keep both.

Sarah, 48

GLP-1 Microdose since Sep '24

From first assessment to optimized protocol, entirely online

No waiting rooms. No referrals. A physician-supervised protocol built around your data.

Complete your health assessment
Step 1

Complete your health assessment

A brief intake covering your health history, goals, and current medications.

GLP-1 Microdose oral tablets

The GLP-1 Microdose Protocol

At lower doses, GLP-1 improves insulin sensitivity, reduces chronic low-grade inflammation, and steadies blood glucose swings. The result is consistent energy, clearer thinking, and a body that responds to diet and movement as it should.

The Metabolic "Glow"

GLP-1 receptors are expressed in the brain, gut, and skin. When metabolic function improves, blood sugar stabilises, inflammation drops, patients consistently report clearer skin, sharper thinking, and a tangible sense of vitality.

Sustainable Energy

Blood sugar swings are one of the most common drivers of afternoon fatigue. By improving insulin sensitivity and moderating post-meal glucose spikes, microdose GLP-1 supports consistent energy from morning to evening.

Reduced Systemic Inflammation

GLP-1 therapy has measurable effects on inflammatory markers including hsCRP and IL-6. Lower chronic inflammation is associated with better cardiovascular health, cognitive function, and long-term metabolic resilience.

Fewer Side Effects by Design

The nausea, muscle loss, and fatigue associated with standard-dose GLP-1 therapy are dose-dependent. Microdosing blunts these risks significantly, and your physician adjusts the protocol if your response warrants it.

HSA/FSA Eligible
Modify or cancel anytime
Longevity lab panels
Expert guidance
$179/mo
4.9
|12,000+ PATIENTS SERVED

Five layers of care
all included at $179/month

Your plan combines physician-prescribed medication, CLIA-certified lab testing, the blēo wearable device, AI coaching, and ongoing physician oversight in one protocol.

GLP-1 Microdose
GLP-1 Microdose

GLP-1 Microdose Medication

Physician-prescribed GLP-1 Microdose, oral or injectable, based on your assessment.

Licensed US physicians
FDA-regulated medications
100% online
Personalized treatment
Lab tests
Free wearable
Ongoing support
Free shipping
Licensed US physicians
FDA-regulated medications
100% online
Personalized treatment
Lab tests
Free wearable
Ongoing support
Free shipping
Licensed US physicians
FDA-regulated medications
100% online
Personalized treatment
Lab tests
Free wearable
Ongoing support
Free shipping

Your physician is with you every step

Every patient has a US-licensed physician who reviews their lab results, interprets their biomarkers, and calibrates their protocol over time. This is not a one-size-fits-all program.

I've had the same GP tell me my bloods were 'normal' for five years while I felt progressively worse. The difference here is that my physician looked at my numbers with context, not just whether they were in range, but what they meant for me.

Claire B.
Claire B.
51, Chicago

My doc at home is great but doesn't specialize in metabolic health. Having a physician who reviews my quarterly labs specifically for longevity markers changes what the data means. I finally feel like someone's reading the whole picture.

James H.
James H.
49, New York

My physician spotted elevated fasting insulin on my first panel. My GP had never tested for it. Two quarters later it's trending down and I can see exactly why on my dashboard.

Maya T.
Maya T.
42, San Diego

I was nervous about a telehealth physician prescribing medication. Then he spent twenty minutes on my first call walking through my labs line by line. My in-person doctor has never done that.

Brian K.
Brian K.
58, Dallas

At my quarterly review my physician adjusted my dose down, not up. She said the data showed I was responding well and a lower dose would reduce side effects without losing progress. That kind of restraint builds trust.

Simone W.
Simone W.
46, Seattle

I sent a message through the portal on a Sunday about a mild headache and got a response from my care team within four hours. They adjusted my hydration guidance and checked in the next day. I've never experienced that level of follow-through.

Lucia G.
Lucia G.
38, Miami

My physician explained why my hsCRP was more important than my cholesterol at this stage. No other doctor had ever prioritized inflammation over the standard lipid panel. That reframing changed how I think about my health.

Troy A.
Troy A.
53, Philadelphia

I was on a different GLP-1 program with no lab work at all. Just a prescription and a follow-up email every month. Here my physician reviews fifty markers before deciding anything. The difference is night and day.

Hannah P.
Hannah P.
37, Raleigh

After my second quarter labs my physician said my metabolic markers had improved enough to lower my dose. I was surprised, but she showed me the data and it made sense. Less medication, same results, fewer side effects.

Omar R.
Omar R.
45, Houston

I've had the same GP tell me my bloods were 'normal' for five years while I felt progressively worse. The difference here is that my physician looked at my numbers with context, not just whether they were in range, but what they meant for me.

Claire B.
Claire B.
51, Chicago

My doc at home is great but doesn't specialize in metabolic health. Having a physician who reviews my quarterly labs specifically for longevity markers changes what the data means. I finally feel like someone's reading the whole picture.

James H.
James H.
49, New York

My physician spotted elevated fasting insulin on my first panel. My GP had never tested for it. Two quarters later it's trending down and I can see exactly why on my dashboard.

Maya T.
Maya T.
42, San Diego

I was nervous about a telehealth physician prescribing medication. Then he spent twenty minutes on my first call walking through my labs line by line. My in-person doctor has never done that.

Brian K.
Brian K.
58, Dallas

At my quarterly review my physician adjusted my dose down, not up. She said the data showed I was responding well and a lower dose would reduce side effects without losing progress. That kind of restraint builds trust.

Simone W.
Simone W.
46, Seattle

I sent a message through the portal on a Sunday about a mild headache and got a response from my care team within four hours. They adjusted my hydration guidance and checked in the next day. I've never experienced that level of follow-through.

Lucia G.
Lucia G.
38, Miami

My physician explained why my hsCRP was more important than my cholesterol at this stage. No other doctor had ever prioritized inflammation over the standard lipid panel. That reframing changed how I think about my health.

Troy A.
Troy A.
53, Philadelphia

I was on a different GLP-1 program with no lab work at all. Just a prescription and a follow-up email every month. Here my physician reviews fifty markers before deciding anything. The difference is night and day.

Hannah P.
Hannah P.
37, Raleigh

After my second quarter labs my physician said my metabolic markers had improved enough to lower my dose. I was surprised, but she showed me the data and it made sense. Less medication, same results, fewer side effects.

Omar R.
Omar R.
45, Houston

My physician explained why my hsCRP was more important than my cholesterol at this stage. No other doctor had ever prioritized inflammation over the standard lipid panel. That reframing changed how I think about my health.

Troy A.
Troy A.
53, Philadelphia

I was on a different GLP-1 program with no lab work at all. Just a prescription and a follow-up email every month. Here my physician reviews fifty markers before deciding anything. The difference is night and day.

Hannah P.
Hannah P.
37, Raleigh

After my second quarter labs my physician said my metabolic markers had improved enough to lower my dose. I was surprised, but she showed me the data and it made sense. Less medication, same results, fewer side effects.

Omar R.
Omar R.
45, Houston

I have PCOS and every other provider I've seen has treated it as a separate issue from my weight. My physician here connected the insulin resistance, the inflammation, and the protocol into one picture. First time that's happened.

Jess D.
Jess D.
36, Tampa

My physician flagged that my sleep quality was dropping based on wearable data, before I even noticed. She adjusted the timing of my dose and within a week my deep sleep was back to baseline. That kind of attention is not normal.

Rina V.
Rina V.
50, Sacramento

I travel for work constantly and was worried about consistency. My physician built the protocol around my schedule, adjusted check-in timing, and made sure my labs could be done at any Quest location. No friction at all.

Elliott M.
Elliott M.
47, Washington DC

I've had the same GP tell me my bloods were 'normal' for five years while I felt progressively worse. The difference here is that my physician looked at my numbers with context, not just whether they were in range, but what they meant for me.

Claire B.
Claire B.
51, Chicago

My doc at home is great but doesn't specialize in metabolic health. Having a physician who reviews my quarterly labs specifically for longevity markers changes what the data means. I finally feel like someone's reading the whole picture.

James H.
James H.
49, New York

My physician spotted elevated fasting insulin on my first panel. My GP had never tested for it. Two quarters later it's trending down and I can see exactly why on my dashboard.

Maya T.
Maya T.
42, San Diego

My physician explained why my hsCRP was more important than my cholesterol at this stage. No other doctor had ever prioritized inflammation over the standard lipid panel. That reframing changed how I think about my health.

Troy A.
Troy A.
53, Philadelphia

I was on a different GLP-1 program with no lab work at all. Just a prescription and a follow-up email every month. Here my physician reviews fifty markers before deciding anything. The difference is night and day.

Hannah P.
Hannah P.
37, Raleigh

After my second quarter labs my physician said my metabolic markers had improved enough to lower my dose. I was surprised, but she showed me the data and it made sense. Less medication, same results, fewer side effects.

Omar R.
Omar R.
45, Houston

I have PCOS and every other provider I've seen has treated it as a separate issue from my weight. My physician here connected the insulin resistance, the inflammation, and the protocol into one picture. First time that's happened.

Jess D.
Jess D.
36, Tampa

My physician flagged that my sleep quality was dropping based on wearable data, before I even noticed. She adjusted the timing of my dose and within a week my deep sleep was back to baseline. That kind of attention is not normal.

Rina V.
Rina V.
50, Sacramento

I travel for work constantly and was worried about consistency. My physician built the protocol around my schedule, adjusted check-in timing, and made sure my labs could be done at any Quest location. No friction at all.

Elliott M.
Elliott M.
47, Washington DC

I've had the same GP tell me my bloods were 'normal' for five years while I felt progressively worse. The difference here is that my physician looked at my numbers with context, not just whether they were in range, but what they meant for me.

Claire B.
Claire B.
51, Chicago

My doc at home is great but doesn't specialize in metabolic health. Having a physician who reviews my quarterly labs specifically for longevity markers changes what the data means. I finally feel like someone's reading the whole picture.

James H.
James H.
49, New York

My physician spotted elevated fasting insulin on my first panel. My GP had never tested for it. Two quarters later it's trending down and I can see exactly why on my dashboard.

Maya T.
Maya T.
42, San Diego

That glow people talk about? It's not a mystery.

GLP-1 Microdose

Woman smiling confidently
Woman feeling her best
Woman enjoying the outdoors at the ocean
Man checking his health progress
Man feeling his best
Woman with warm expression
Woman feeling energized and confident
Man smiling confidently

More than medication

Access your GLP-1 Microdose plan with a comprehensive approach designed for long-term metabolic health.

Comprehensive metabolic wellness — physician, medication, and monitoring
Certified physicians
Complete plan
24/7 access to our Care Team
100% online
Dosage and protocol adjustments, as needed
Continuous longevity monitoring
Personal nutrition and lifestyle coaching

Reviews

5/5
247 Reviews
Tanisha R.

Was paying $1,300/mo before I found this

I spent eleven months at a weight loss clinic paying over $1,300 a month for the same class of medication with zero lab work included. Here I get the medication, labs, wearable, and a physician who reviews everything for $179. I wish I had found this first.

Greg P.

Standard dose wrecked me, microdose was the fix

I tried a standard GLP-1 dose through another provider and the nausea was unbearable. Felt like severe morning sickness for three weeks straight. Switched to the microdose protocol here and I have had zero GI issues. Still losing weight, just without the misery.

Monica S.

The food noise just stopped

I used to plan every meal hours in advance and think about snacks all afternoon. By week three on the microdose, that mental chatter went quiet. I eat when I am hungry and move on. My husband noticed before I even said anything.

Frequently askedquestions aboutGLP-1 Microdose

What's your main reason for exploring GLP-1 Microdose?

Important Safety Information

GLP-1 medications are FDA-approved under certain brand indications. Compounded versions are not FDA-approved.

Prescription products are subject to healthcare provider approval following an online consultation.

Common side effects may include nausea, vomiting, diarrhea, and constipation, particularly during dose escalation.

Do not take GLP-1 therapies if you have a personal or family history of medullary thyroid carcinoma or MEN 2. Seek urgent care for severe abdominal pain or signs of allergic reaction.

Results vary by person and protocol. Compounded medications are not FDA-approved and are prepared by a licensed pharmacy based on a provider's prescription.

Longevity Direct

The GLP-1 Microdose protocol

Physician-guided protocols with labs, tracking, and ongoing support

LegitScript Certification

© 2026 Longr Holdings Inc.

142 West 57th Street | New York, NY 10019

Prescription products require an online consultation with a physician who will determine if a prescription is appropriate. See product page for important safety information. Benefits outlined on Longevity Direct are based on 3rd party studies.

Medical statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. If you are in need of emergency medical attention, please call 911 immediately.