Physician-prescribed GLP-1 Microdose

Feel like yourself again.Energy, clarity, and weight. Sorted.

A lower-dose GLP-1 protocol prescribed by a US physician.
What patients notice within the first few weeks:

  • Steady energy from morning to evening. no afternoon crash
  • Gradual, sustainable weight changes without muscle loss
  • Fewer side effects than standard GLP-1 dosing
  • 50+ biomarkers tracked so you see exactly what's improving
$179/mo
Starting at $179/mo
Cancel anytime
GLP-1 Microdose health protocol

AS FEATURED IN

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The power of GLP-1 Microdose

0/10

Patients report improved sense of wellbeing on GLP-1 protocols.*

0%

Report more consistent energy throughout the day.*

*Based on patient-reported outcomes.

Is a GLP-1 Microdose right for me?

This protocol is designed for people who want real metabolic support, not crash-diet results, with a physician who reviews their lab data.

Selected: Lose stubborn weight without losing muscle

Patient maintaining strength while losing weight

I've lost about 14 pounds over four months. My trainer said my muscle mass went up slightly. I didn't expect to keep both.

Michelle, 52

GLP-1 Microdose since Aug '24

From first assessment to optimized protocol, entirely online

No waiting rooms. No referrals. A physician-supervised protocol built around your data.

Complete your health assessment
Step 1

Complete your health assessment

A brief intake covering your health history, goals, and current medications. Takes under ten minutes.

Ready to see if you qualify?

GLP-1 Microdose oral tablets

The GLP-1 Microdose Protocol

At lower doses, GLP-1 improves insulin sensitivity, reduces chronic low-grade inflammation, and steadies blood glucose swings. The result is consistent energy, clearer thinking, and a body that responds to diet and movement as it should.

The Metabolic Glow

GLP-1 receptors are expressed in the brain, gut, and skin. When metabolic function improves, blood sugar stabilises, inflammation drops, patients consistently report clearer skin, sharper thinking, and a tangible sense of vitality.

All-Day Energy

Blood sugar swings are one of the most common drivers of afternoon fatigue. By improving insulin sensitivity and moderating post-meal glucose spikes, microdose GLP-1 supports consistent energy from morning to evening.

Reduced Systemic Inflammation

GLP-1 therapy has measurable effects on inflammatory markers including hsCRP and IL-6. Lower chronic inflammation is associated with better cardiovascular health, cognitive function, and long-term metabolic resilience.

Fewer Side Effects by Design

The nausea, muscle loss, and fatigue associated with standard-dose GLP-1 therapy are dose-dependent. Microdosing blunts these risks significantly, and your physician adjusts the protocol if your response warrants it.

HSA/FSA Eligible
Modify or cancel anytime
Longevity lab panels
Expert guidance
$179/mo
4.9
|500+ PATIENTS SERVED

Five layers of care, all included at $179/month

Your plan combines physician-prescribed medication, CLIA-certified lab testing, the blēo wearable device, AI coaching, and ongoing physician oversight in one protocol.

GLP-1 Microdose
GLP-1 Microdose

GLP-1 Microdose Medication

Physician-prescribed compounded semaglutide or tirzepatide, oral or injectable, based on your assessment.

Your physician is with you every step

Every patient has a US-licensed physician who reviews their lab results, interprets their biomarkers, and calibrates their protocol over time. This is not a one-size-fits-all program.

I've had the same GP tell me my bloods were 'normal' for five years while I felt progressively worse. The difference here is that my physician looked at my numbers with context, not just whether they were in range, but what they meant for me.

Claire B.
Claire B.
51, Chicago

My doc at home is great but doesn't specialize in metabolic health. Having a physician who reviews my quarterly labs specifically for longevity markers changes what the data means. I finally feel like someone's reading the whole picture.

James H.
James H.
49, New York

I've had the same GP tell me my bloods were 'normal' for five years while I felt progressively worse. The difference here is that my physician looked at my numbers with context, not just whether they were in range, but what they meant for me.

Claire B.
Claire B.
51, Chicago

My doc at home is great but doesn't specialize in metabolic health. Having a physician who reviews my quarterly labs specifically for longevity markers changes what the data means. I finally feel like someone's reading the whole picture.

James H.
James H.
49, New York

I've had the same GP tell me my bloods were 'normal' for five years while I felt progressively worse. The difference here is that my physician looked at my numbers with context, not just whether they were in range, but what they meant for me.

Claire B.
Claire B.
51, Chicago

My doc at home is great but doesn't specialize in metabolic health. Having a physician who reviews my quarterly labs specifically for longevity markers changes what the data means. I finally feel like someone's reading the whole picture.

James H.
James H.
49, New York

I've had the same GP tell me my bloods were 'normal' for five years while I felt progressively worse. The difference here is that my physician looked at my numbers with context, not just whether they were in range, but what they meant for me.

Claire B.
Claire B.
51, Chicago

My doc at home is great but doesn't specialize in metabolic health. Having a physician who reviews my quarterly labs specifically for longevity markers changes what the data means. I finally feel like someone's reading the whole picture.

James H.
James H.
49, New York

I've had the same GP tell me my bloods were 'normal' for five years while I felt progressively worse. The difference here is that my physician looked at my numbers with context, not just whether they were in range, but what they meant for me.

Claire B.
Claire B.
51, Chicago

I've had the same GP tell me my bloods were 'normal' for five years while I felt progressively worse. The difference here is that my physician looked at my numbers with context, not just whether they were in range, but what they meant for me.

Claire B.
Claire B.
51, Chicago

My doc at home is great but doesn't specialize in metabolic health. Having a physician who reviews my quarterly labs specifically for longevity markers changes what the data means. I finally feel like someone's reading the whole picture.

James H.
James H.
49, New York

I've had the same GP tell me my bloods were 'normal' for five years while I felt progressively worse. The difference here is that my physician looked at my numbers with context, not just whether they were in range, but what they meant for me.

Claire B.
Claire B.
51, Chicago

My doc at home is great but doesn't specialize in metabolic health. Having a physician who reviews my quarterly labs specifically for longevity markers changes what the data means. I finally feel like someone's reading the whole picture.

James H.
James H.
49, New York

I've had the same GP tell me my bloods were 'normal' for five years while I felt progressively worse. The difference here is that my physician looked at my numbers with context, not just whether they were in range, but what they meant for me.

Claire B.
Claire B.
51, Chicago

My doc at home is great but doesn't specialize in metabolic health. Having a physician who reviews my quarterly labs specifically for longevity markers changes what the data means. I finally feel like someone's reading the whole picture.

James H.
James H.
49, New York

I've had the same GP tell me my bloods were 'normal' for five years while I felt progressively worse. The difference here is that my physician looked at my numbers with context, not just whether they were in range, but what they meant for me.

Claire B.
Claire B.
51, Chicago

My doc at home is great but doesn't specialize in metabolic health. Having a physician who reviews my quarterly labs specifically for longevity markers changes what the data means. I finally feel like someone's reading the whole picture.

James H.
James H.
49, New York

I've had the same GP tell me my bloods were 'normal' for five years while I felt progressively worse. The difference here is that my physician looked at my numbers with context, not just whether they were in range, but what they meant for me.

Claire B.
Claire B.
51, Chicago

My doc at home is great but doesn't specialize in metabolic health. Having a physician who reviews my quarterly labs specifically for longevity markers changes what the data means. I finally feel like someone's reading the whole picture.

James H.
James H.
49, New York

I've had the same GP tell me my bloods were 'normal' for five years while I felt progressively worse. The difference here is that my physician looked at my numbers with context, not just whether they were in range, but what they meant for me.

Claire B.
Claire B.
51, Chicago

My doc at home is great but doesn't specialize in metabolic health. Having a physician who reviews my quarterly labs specifically for longevity markers changes what the data means. I finally feel like someone's reading the whole picture.

James H.
James H.
49, New York

I've had the same GP tell me my bloods were 'normal' for five years while I felt progressively worse. The difference here is that my physician looked at my numbers with context, not just whether they were in range, but what they meant for me.

Claire B.
Claire B.
51, Chicago

My doc at home is great but doesn't specialize in metabolic health. Having a physician who reviews my quarterly labs specifically for longevity markers changes what the data means. I finally feel like someone's reading the whole picture.

James H.
James H.
49, New York

I've had the same GP tell me my bloods were 'normal' for five years while I felt progressively worse. The difference here is that my physician looked at my numbers with context, not just whether they were in range, but what they meant for me.

Claire B.
Claire B.
51, Chicago

My doc at home is great but doesn't specialize in metabolic health. Having a physician who reviews my quarterly labs specifically for longevity markers changes what the data means. I finally feel like someone's reading the whole picture.

James H.
James H.
49, New York

I've had the same GP tell me my bloods were 'normal' for five years while I felt progressively worse. The difference here is that my physician looked at my numbers with context, not just whether they were in range, but what they meant for me.

Claire B.
Claire B.
51, Chicago

My doc at home is great but doesn't specialize in metabolic health. Having a physician who reviews my quarterly labs specifically for longevity markers changes what the data means. I finally feel like someone's reading the whole picture.

James H.
James H.
49, New York

My doc at home is great but doesn't specialize in metabolic health. Having a physician who reviews my quarterly labs specifically for longevity markers changes what the data means. I finally feel like someone's reading the whole picture.

James H.
James H.
49, New York

I've had the same GP tell me my bloods were 'normal' for five years while I felt progressively worse. The difference here is that my physician looked at my numbers with context, not just whether they were in range, but what they meant for me.

Claire B.
Claire B.
51, Chicago

My doc at home is great but doesn't specialize in metabolic health. Having a physician who reviews my quarterly labs specifically for longevity markers changes what the data means. I finally feel like someone's reading the whole picture.

James H.
James H.
49, New York

I've had the same GP tell me my bloods were 'normal' for five years while I felt progressively worse. The difference here is that my physician looked at my numbers with context, not just whether they were in range, but what they meant for me.

Claire B.
Claire B.
51, Chicago

My doc at home is great but doesn't specialize in metabolic health. Having a physician who reviews my quarterly labs specifically for longevity markers changes what the data means. I finally feel like someone's reading the whole picture.

James H.
James H.
49, New York

I've had the same GP tell me my bloods were 'normal' for five years while I felt progressively worse. The difference here is that my physician looked at my numbers with context, not just whether they were in range, but what they meant for me.

Claire B.
Claire B.
51, Chicago

My doc at home is great but doesn't specialize in metabolic health. Having a physician who reviews my quarterly labs specifically for longevity markers changes what the data means. I finally feel like someone's reading the whole picture.

James H.
James H.
49, New York

I've had the same GP tell me my bloods were 'normal' for five years while I felt progressively worse. The difference here is that my physician looked at my numbers with context, not just whether they were in range, but what they meant for me.

Claire B.
Claire B.
51, Chicago

My doc at home is great but doesn't specialize in metabolic health. Having a physician who reviews my quarterly labs specifically for longevity markers changes what the data means. I finally feel like someone's reading the whole picture.

James H.
James H.
49, New York
Licensed US physicians
FDA-regulated medications
100% online
Personalized treatment
Lab tests
Free wearable
Ongoing support
Free shipping
Licensed US physicians
FDA-regulated medications
100% online
Personalized treatment
Lab tests
Free wearable
Ongoing support
Free shipping
Licensed US physicians
FDA-regulated medications
100% online
Personalized treatment
Lab tests
Free wearable
Ongoing support
Free shipping

That glow people talk about? It's not a mystery.

GLP-1 Microdose

Woman smiling confidently
Woman feeling her best
Woman enjoying the outdoors at the ocean
Man checking his health progress
Man feeling his best
Woman with warm expression
Man working with energy and focus
Man smiling confidently

More than medication

Access your GLP-1 Microdose plan with a comprehensive approach designed for long-term metabolic health.

Comprehensive metabolic plan: physician, medication, and monitoring
Certified physicians
Complete plan
24/7 access to our Care Team
100% online
Dosage and protocol adjustments, as needed
Continuous longevity monitoring
Personal nutrition and lifestyle coaching

Reviews

5/5
127 Reviews
Amani L.

Energy and clarity, not what I expected from GLP-1

I joined for energy, not weight loss. Six weeks in, the difference is real. Afternoons are productive again, my skin looks better, and my physician explained what was changing and why. The inflammation finding at baseline was the key thing nobody had flagged before.

Jenna K.

The results my friends described, without the rough start

My friends had a tough first month on GLP-1. I had one mild day and then nothing. The slower titration is the difference. By week six I was 12 lbs down and hadn't felt restricted once. My physician responded every time I had a question.

Priya N.

My colleagues noticed before I told them

Week four, people at work started asking what I was doing differently. My physician found elevated inflammation at baseline, something nobody had caught before. Six weeks later, I have a visible answer to give them.

Frequently askedquestions aboutGLP-1 Microdose

What's your main reason for exploring GLP-1 Microdose?

Important Safety Information

GLP-1 medications are FDA-approved under certain brand indications. Compounded versions are not FDA-approved.

Prescription products are subject to healthcare provider approval following an online consultation.

Common side effects may include nausea, vomiting, diarrhea, and constipation, particularly during dose escalation.

Do not take GLP-1 therapies if you have a personal or family history of medullary thyroid carcinoma or MEN 2. Seek urgent care for severe abdominal pain or signs of allergic reaction.

Results vary by person and protocol. Compounded medications are not FDA-approved and are prepared by a licensed pharmacy based on a provider's prescription.

Longevity Direct

The GLP-1 Microdose protocol

Physician-guided protocols with labs, tracking, and ongoing support

LegitScript Certification

© 2026 Longr Holdings Inc.

142 West 57th Street | New York, NY 10019

Prescription products require an online consultation with a physician who will determine if a prescription is appropriate. See product page for important safety information. Benefits outlined on Longevity Direct are based on 3rd party studies.

Medical statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. If you are in need of emergency medical attention, please call 911 immediately.