Longevity 360

The clinic experience from your home.

A seamless experience, medications delivered straight to your door, online access to experienced US physicians, coaching, testing, optimization, and monitoring – all supported by our unbeatable care.

No waiting rooms, no hidden fees.

All included in your plan.

Medication

Science-backed treatments are the cornerstone of any effective longevity program.

Diligently prescribed to suit your needs, your medication targets the underlying mechanisms of aging to help you thrive.

The first longevity wearable to harness the power of biometric AI. Usually $149, included in your plan. 

Refining millions of unique longevity signals, it unlocks clear, actionable guidance tailored to your unique longevity profile.

Your all-in-one coach for fitness, nutrition, sleep, and mindfulness.

Powered by data and designed for results, it turns insights into meaningful longevity progress tracking. 

Lab Tests

Understanding your body’s inner workings is the cornerstone of effective longevity planning.
 

If you choose a Rapamycin plan, you will take comprehensive lab tests at week 6, including CBC, CMP, Lipid Panel, hs-CRP, and Hemoglobin A1c.

Physician On Demand

For queries related to your medication, our physicians are available to provide clear guidance and support.

They are here to address your concerns and ensure your treatment aligns with your unique health profile.

Popular medications
and protocols

Targeted, clinically validated treatments to address the root causes of aging.

Prescribed to keep aging on the defensive, it’s the solid bedrock every effective longevity plan needs.

From $75/month

From $35/month

From $299/month

Private care,
100% online

Online access – anywhere, anytime. Managed securely through your personal online portal.

Clinically validated
medications

Physician trusted, clinically tested medications, to meet your unique needs.

Prescribed by
licensed providers

Consultations and continuous support from licensed providers, across all 50 states.

From US Pharmacies
to your door

US based, certified pharmacies deliver your medication with free, discreet, shipping to your door.

Preventing age-related disease starts here.

It takes more than medication alone.

Achieving lasting longevity is deeply rewarding but requires commitment.

That’s why we’re dedicated to providing the complete range of science-backed pathways you need to unlock your longevity.

General Longevity

Live well, longer

Heart Health

Strengthen every beat

Glucose Control

Balance from within

Cognitive Function

Sharpen your mind

Blood Pressure

Stay steady, stay strong

Immune support

Empower your resilience

Your Journey

Simple, tailored, results-driven.

Your 5-step journey makes it easy to take control of aging and achieve your best, healthiest self.

Research

Access clinically validated medications redefining how we approach aging.

How does Rapamycin work?

Potential
side effects

How does Metformin work?

Potential
side effects

How do GLP-1s work?

Potential
side effects

Targeting aging at its source - sounds futuristic, right?

Rapamycin is known as the darling of longevity science for a reason.

It modulates the mTOR pathway, your body’s cellular control center, shifting it into repair mode.

The studied results?..

Better cellular renewal, reduced inflammation, and potential protection against age-related diseases like cardiovascular decline, neurodegeneration, and even certain cancers.

Curious about Rapamycin for your longevity? ⤵️

https://longevity.direct/

#LongevityMedicine #Rapamycin #HealthyAging

(Please note: Rapamycin is not FDA-approved for anti-aging purposes)
Your VO2 max - how efficiently your body uses oxygen during exercise - isn’t just for athletes. 

It’s actually a better predictor of longevity than traditional health metrics like BMI or blood pressure (American Heart Association, 2016). 

This single number provides key insights into your risk for heart disease, cancer, and other chronic illnesses.

🔹 Men in the top 5% of VO2 max levels live nearly 5 years longer than those in the bottom 5%. Each 1 mL/kg/min increase adds around 45 days to life expectancy (Frontiers in Bioscience, 2018).

🔹 A high VO2 max levels are linked to a 21% lower risk of death from all causes over decades (Journal of Applied Physiology, 2022).

At Longevity Direct, we make it easy to track and improve this vital metric.

With The Longevity AI, included in your plan, connect a supported wearable to get personalized coaching to optimize your VO2 max.

It’s science, made personal - because longevity shouldn’t be guesswork ⤵️

https://longevity.direct

#VO2Max #Longevity #HealthTech
The rising tide of chronic disease is reshaping healthcare - and not for the better.

Chronic conditions now drive 90% of U.S. healthcare costs.

Astonishingly, only 2.9% of spending goes toward prevention - a decline from 3.7% in 2000 (Health System Tracker).

It’s time for a shift.

At Longevity Direct, your plan guarantees a comprehensive, prevention-first approach:

🔹 Medication: Clinically proven, targeting longevity and reducing chronic disease risks.

🔹 blēo: The first longevity wearable, linking your daily habits to long-term health outcomes.

🔹 The Longevity AI Coach: Data-driven, personal coaching to reduce your biological age.

🔹 Lab Tests: Advanced biomarker analysis to uncover risks and optimize your longevity strategy.

🔹 Physicians On Demand: Accessible, expert-led guidance when and wherever you need it.

Prevention isn’t just better - it’s smarter.

Ready to take the first step? ⤵️

https://longevity.direct/

#ChronicDisease #HealthCrisis #PreventiveHealth
Your body speaks; are you listening? 

Heart Rate Variability (HRV) is a powerful indicator of how well your body handles stress and recovers - your longevity. 

If you're noticing dips, it could mean it's time to adjust your routine, prioritize recovery, or optimize your sleep.

The Longevity AI coach, included in your Longevity Direct plan, doesn't just track - it guides. Uncover what your HRV is telling us and create a plan to help you thrive.

Ready to tune into your body’s longevity signals? ⤵️

https://longevity.direct/

#LongevityHealth #BiometricData #HRV
Metformin, the diabetes drug that’s gaining major attention for its longevity potential. 

With the TAME Trial underway, the science behind Metformin’s anti-aging effects is looking more exciting than ever.

🔹 Blood Sugar Balance: It helps maintain healthy blood glucose levels, which is key for metabolic health as we age.

🔹 Heart Health: Studies have linked it with reduced cardiovascular risk, supporting a healthier heart as we age. 

🔹 Cognitive Support: Evidence suggests use is associated with a lower risk of cognitive decline. 

🔹 Cancer Risk Reduction: Meta-analyses show potential for reduced risk of certain cancers, including gastrointestinal and blood cancers. 

🔹 Anti-Inflammatory Benefits: Its anti-inflammatory effects may help combat cellular damage linked to aging.

Metformin is undoubtedly transforming how we think about growing older.

Interested in the science behind it? ⤵️

https://longevity.direct/

#Metformin #TAME #LongevityHealth

(Please note: Metformin is not currently FDA-approved for anti-aging purposes.)
This error message is only visible to WordPress admins
Error: Access Token is not valid or has expired. Feed will not update.

Is Rapamycin right for me?

If you’re looking to age better – whether by optimizing your health or addressing early signs of decline – Rapamycin could be a meaningful step forward.

By targeting the mTOR pathway, Rapamycin helps shift your body’s focus from growth to repair, promoting cellular health and reducing inflammation.

Research suggests it may improve immune function, support cognitive health, and lower risks of age-related diseases like cardiovascular decline and cancer.

While Rapamycin is prescribed “off-label” for longevity purposes, it’s backed by extensive studies and careful medical oversight ensures it’s safe and effective.

At Longevity Direct, we tailor your treatment plan through a detailed intake process, supported blēo and The Longevity AI to track your progress.

Once approved, your plan evolves to meet your needs.

Safety

Rapamycin is administered in low, intermittent doses to minimize risks.

Any potential side effects, such as mild digestive upset or temporary immune changes, are rare and manageable with proper care.

Our team ensures you’re supported every step of the way.

Important to know

Rapamycin is not FDA-approved for longevity or anti-aging purposes.

Prescriptions are approved through an online consultation with a licensed healthcare provider.

What are the studied benefits of Rapamycin?

Rapamycin is one of the most studied compounds in longevity science, attracting significant interest from researchers worldwide.

With decades of research across organisms from yeast to mammals, it has consistently demonstrated its potential to extend lifespan and improve healthspan. 

  • Proven to extend lifespan: Rapamycin has extended lifespan in every organism tested, from yeast to mammals, by targeting the mTOR pathway. (Source: EUROPE PMC)

 

  • Improves healthspan: Rapamycin slows age-related decline, supporting healthier cells and delaying aging-associated conditions. (Source: EUROPE PMC)

 

  • Boosts immune function: Enhances immune response, particularly in older adults, by promoting cellular repair and reducing inflammation.

 

  • Reduces risks of specific conditions:
    • Cognitive protection: May slow cognitive decline by reducing neuroinflammation and supporting brain health. (Source: OXFORD ACADEMIC)
    • Metabolic health: Improves insulin sensitivity and reduces systemic inflammation linked to metabolic disorders. (Source: PLOS JOURNALS)
    • Organ health: Protects organs like the kidneys and liver from age-related damage via cellular repair mechanisms. (Source: PLOS JOURNALS)
    • Cancer risk reduction: Slows the progression of certain cancers by inhibiting cell proliferation and activating autophagy. (Source: PLOS JOURNALS)
    • Joint and bone health: Research suggests it may alleviate arthritis symptoms and improve bone density. (Source: PLOS JOURNALS)

How does Rapaymcin work?

Rapamycin slows aging by targeting the mTOR pathway, shifting the body’s focus from growth to repair. It promotes cellular recycling, reduces overgrowth linked to disease, and enhances resilience to stress.

Imagine your body as a city, bustling with activity.

Cells are the workers, and mTOR (mechanistic target of rapamycin) is the city planner, deciding where to focus resources – building new structures, cleaning up waste, or repairing old ones.

As we age, mTOR often prioritizes building (cell growth) over maintenance (cellular repair), leading to “clutter” in our bodies that contributes to aging and disease.

This is where Rapamycin comes in.

It acts like a wise advisor to mTOR, convincing it to slow down unnecessary growth projects and focus on cleanup and repair instead.

Specifically, Rapamycin:

  • Activates cellular recycling (autophagy):
    Think of autophagy as the city’s waste management system. Damaged parts of cells are broken down and reused, keeping the system efficient and healthy.

  • Reduces harmful overgrowth:
    Overactive mTOR has been linked to diseases such as cancer, cardiovascular disease, and neurodegenerative conditions like Alzheimer’s. By dialing back excessive growth signals, Rapamycin helps prevent these issues.

  • Supports stress resilience:
    When cells are less focused on growing, they’re better equipped to handle stress, repair damage, and maintain long-term health.

What are the potential side effects of Rapamycin?

Temporary immune changes: Rapamycin can cause mild immunosuppression, making it essential to follow dosing guidelines closely.

Digestive issues: Some users report mild nausea, diarrhea, or stomach discomfort.

Mouth sores: A common but manageable side effect, especially at higher doses.

Fatigue or headaches: Occasionally experienced but typically mild.

With proper medical oversight and careful dosing, these risks are both manageable and avoidable. 

At Longevity Direct, our team closely monitors your progress to ensure the safest, most effective treatment plan for your needs.