Prescription Compounds

We focus on delivering select medicines, through US physician led prescription, leveraging a wealth of specialist AI analyzed research. 

Metformin

Metformin activates the AMPK pathway, which is pivotal in regulating metabolism and cellular energy homeostasis. Studies, indicate that metformin can extend lifespan by improving metabolic efficiency and delaying the onset of metabolic diseases.

Rapamycin

Rapamycin inhibits the mTOR pathway, which plays a crucial role in cell growth and aging. Research, primarily in animal models, shows that rapamycin can increase lifespan and improve healthspan by delaying the onset of age-related diseases.

Longevity 360

Your Complete Longevity Suite​

Your all-inclusive suite featuring expert guidance, the sensor-packed blēo longevity band, personalized AI coaching, lab testing, and discounted access to the powerful Saints One supplement program.

Lab Tests & Biomarkers

We specialize in providing cutting-edge biomarker panels, each tailored to your unique health needs, through a swift and secure AI-enhanced platform, drawing upon a vast repository of expert-curated medical insights.

+2,500 Biomarkers

A full suite of longevity Biomarkers. Includes both Blood and Swab Panels with enhanced AI Longevity profiling.

+1,000 Biomarkers

Comprehensive longevity saliva tests. Genetic and epigenetic DNA Testing.

+100 Biomarkers

A full suite of longevity blood work. 27 Tests – 105 Biomarkers.

How Longevity Direct Works

Quick access to the latest science, medicine and media to understand how and why Rapamycin and Metformin are the subject of landmark studies and global headlines.

Beyond Prescriptions

At Longevity Direct, we know the first script is just the beginning. Living a longer, healthier life is a long term commitment, so we offer all the essential, inclusive services you’ll need on your journey. Our focus is on providing a complete solution, and a longevity protocol that is safe and effective.

Lab Test

A simple, at home swab test for a complete, needle free body diagnostic through our certified partner independent lab.

Biological Age Clock

Advanced AI powers your biological age clock, with a simple, easy to use app to compare it with your chronological age.

Progress Tracking & Coaching

Keep ahead of the longevity curve with unlimited physician and prescription access, longevity coaching and our experts.

Your Journey

Enjoy a seamless experience, from consulting with an experienced US physician, through testing, optimization and monitoring, to our unbeatable support.

We focus on delivering select medicines, through US physician led prescription, leveraging a wealth of specialist AI analyzed research. 

The Science of Autophagy

Autophagy, a cellular recycling process, holds great promise in the field of longevity medicine. This natural mechanism allows cells to break down and remove damaged components, promoting cellular renewal and maintaining optimal function. By inducing autophagy through interventions like calorie restriction, fasting, and certain compounds, we can potentially slow the aging process and reduce the risk of age-related diseases. Research suggests that enhancing autophagy may extend lifespan by improving cellular resilience, reducing inflammation, and optimizing metabolic health. As we continue to unravel the complex mechanisms of autophagy, we move closer to harnessing its potential for promoting longevity and healthspan.

The Science of Metabolic Health

Metabolic health lies at the core of longevity and healthspan. Maintaining optimal insulin sensitivity, glucose regulation, and mitochondrial function is crucial for preventing age-related diseases and promoting healthy aging. Interventions like acarbose, which helps regulate glucose spikes and improve gut microbiome composition, have shown promise in enhancing metabolic health and extending lifespan. Additionally, strategies such as calorie restriction, intermittent fasting, and exercise can improve insulin signaling, reduce inflammation, and optimize cellular energy production. By targeting the underlying mechanisms of metabolic dysfunction, we can unlock the potential for increased longevity and improved quality of life in our later years.

The Science of Cellular Senescence

Cellular senescence, a hallmark of aging, involves the accumulation of damaged or dysfunctional cells that no longer divide but persist in tissues, contributing to inflammation and age-related diseases. Senescent cells secrete pro-inflammatory factors, disrupt tissue homeostasis, and accelerate the aging process. Targeting cellular senescence has emerged as a promising approach in longevity medicine. Compounds like rapamycin, which inhibits the mTOR pathway, have been shown to reduce senescent cell burden and extend lifespan in animal models. Senolytics, drugs that selectively eliminate senescent cells, are also being explored as potential therapies to promote healthy aging. By understanding and addressing cellular senescence, we can develop targeted interventions to delay aging and prevent age-related pathologies.

Metformin in aging and aging-related diseases: clinical applications and relevant mechanisms

Aging is a natural process, which plays a critical role in the pathogenesis of a variety of diseases, i.e., aging-related diseases, such as diabetes, osteoarthritis, Alzheimer disease, cardiovascular diseases, cancers, obesity and other metabolic abnormalities. 

This company with anti-aging drug is secretly preparing for Trump’s New FDA

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This company with anti-aging drug is secretly preparing for Trump’s New FDA

As trump shakes up the white house, pharma and biotech are on edge. While the media talks Obamacare, it turns out that Trumps new FDA…

Metformin in aging and aging-related diseases: clinical applications and relevant mechanisms

Aging is a natural process, which plays a critical role in the pathogenesis of a variety of diseases, i.e., aging-related diseases, such as diabetes, osteoarthritis, Alzheimer disease, cardiovascular diseases, cancers, obesity and other metabolic abnormalities. 

Your complete longevity suite​

Experienced US based doctors and medical professionals.
Help, advice and guidance from longevity experts.
Integrated app, AI technology

Why Our Patients Love Longevity Direct

Our Patient Community

Learn from your peers and our experts and join in the most active longevity online community out there. We’re helping to build a repository of advice, information and opinion from the people who matter – patients.

Medicine Lab Testing

We carefully select compounds from the world’s top pharmaceutical producers, and lab test for purity, potency and bioavailability. This ensures maximum absorbion into the body. We base our testing on pharmacokinetic parameters: Cmax and Tmax. These tell us the how effectively and how quickly the drug is absorbed.

Personal Testing

We believe in personalized care and thus, offer our patients the option to stay on track of their intake through testing. This enables us to understand each patient’s unique absorption profile of the medication, taking into account the variability of their biology. This approach ensures that our patients receive the most effective therapeutic regimen tailored to their individual needs.

Complete Patient Intake Form

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