General Questions

Longevity Direct is your complete online longevity clinic from home.

We make it simple and cost-effective to access clinically validated, US-prescribed longevity medications, advanced biomarker testing, AI-powered coaching, and personalized treatment plans – all from the comfort of your home.

  1. Complete an online health evaluation.
  2. A licensed US-based physician reviews your information and recommends a personalized plan.
  3. Approve your plan, and we’ll ship your medications directly to your door.
  4. Enjoy ongoing access to physicians, labs, and AI-powered insights to monitor and optimize your progress.

Your Longevity Direct plan is a seamless, all-in-one solution designed to help you take control of aging.

Here’s what’s included:

  • Medication: Clinically validated treatments prescribed by experienced US physicians to target the underlying mechanisms of aging and help you thrive.
  • Wearable: The first AI-powered longevity wearable, included in your plan (normally $149). It refines millions of biometric signals to deliver clear, actionable insights tailored to your unique longevity profile.
  • AI Coach: A personalized coach for fitness, nutrition, sleep, and mindfulness. Powered by your data, it transforms insights into meaningful progress and tracks your longevity journey.
  • Lab Tests: Where necessary, advanced lab tests  longevity plan, ensuring your program is as unique as you are.
  • Physician On Demand: For queries related to your medication, our physicians are available to provide clear guidance and support.

With no waiting rooms, no hidden fees, and everything delivered straight to your door, your Longevity Direct plan offers unbeatable care for lasting results.

Medication-Specific Questions

The Rapamycin Protocol includes:

  • Personalized dosage recommendations, tailored to your biomarkers and health history.
  • Medications delivered directly to your door from certified US pharmacies.
  • Regular lab testing to monitor progress and ensure your plan is on track.
  • Full access to The Longevity AI, offering real-time insights and optimization.
  • Ongoing support from our licensed medical team, ensuring personalized care every step of the way.

The Metformin Protocol includes:

  • Customized dosage recommendations based on your metabolic health and longevity goals.
  • Metformin delivered directly to your door from trusted US pharmacies.
  • Routine lab testing to track your glucose management and overall health progress.
  • Access to The Longevity AI for personalized insights and ongoing plan adjustments.
  • Expert guidance and unlimited support from your dedicated care team, including licensed US physicians.

Rapamycin may:

  • Target the mTOR pathway to slow aging and enhance cellular repair.
  • Activate autophagy to clear damaged cells, promoting healthier aging.
  • Reduce inflammation and lower risks of age-related diseases, such as cardiovascular disease and certain cancers.
  • Support cognitive health by lowering neuroinflammation and reducing the risk of cognitive decline.
  • Enhance immune function, particularly in older adults, by balancing immune response.

Metformin may:

  • Activate longevity pathways for a longer, healthier life.
  • Enhance mitochondrial function and nutrient sensing, optimizing energy production and cellular repair.
  • Reduce inflammation and cell senescence, lowering risks of diabetes, kidney disease, and certain cancers.
  • Support brain health by reducing the risk of cognitive decline and dementia.
  • Improve metabolic health, helping to control glucose levels and promote weight loss (5-7%).
  • Rapamycin: Typically starts at 3 mg weekly, gradually increasing to 5–8 mg based on your response and goals.
  • Metformin: Doses range from 500 to 1,000 mg daily, depending on your medical history and physician’s recommendations.

How Your Plan Works

Your journey includes:

  1. Completing a detailed intake form.
  2. Medical review and treatment approval.
  3. Medications and tools (like blēo) delivered to your door.
  4. Regular testing and data-driven updates to your plan.
  5. Ongoing access to expert support and monitoring.

Our online consultation process is fast and easy.

After completing your health evaluation, a licensed US physician will review your information and recommend a plan, usually within 24–48 hours.

Once your plan is approved, medications are shipped directly to your door from certified US pharmacies.

It typically takes 2 days for pharmacy processing and an additional 2–3 days for shipping.

We ship to all 50 US states.

You can pause or cancel anytime by:

  • Logging into your patient portal.
  • Navigating to your subscription settings.
  • Making changes directly in your account.

For further assistance, contact our support team – [email protected].

Safety & Privacy

We source medications from US-certified pharmacies and lab-test for purity, potency, and bioavailability.

Regular monitoring ensures your plan remains safe and effective.

Your medical information is encrypted and accessed only by authorized medical professionals.

We use advanced security measures to safeguard your data.

Costs & Payments

Plans start at less than $1 per day, with no lock-in contracts.

Pricing varies based on your selected medications and additional services like advanced biomarker testing.

We accept major credit cards, including:

  • Visa
  • Mastercard
  • American Express
  • Google Pay
  • Apple Pay

Your card will be charged once your plan is approved by a physician.

Contact & Support

  • Prescription Enquiries: For questions related to prescriptions, call +(1) 415-933-3453 (9:00 AM – 5:00 PM ET, Monday to Friday).
  • Customer Support: For all other inquiries, email us at [email protected].

Our prescription enquiry line is available Monday through Friday, 9:00 AM – 5:00 PM Eastern Time.

Contact

Questions, suggestions, reflections?

Fill out the form below and a member of our team well get back to you as soon as possible.

Contact Form (#14)

How does Rapaymcin work?

Rapamycin slows aging by targeting the mTOR pathway, shifting the body’s focus from growth to repair. It promotes cellular recycling, reduces overgrowth linked to disease, and enhances resilience to stress.

Imagine your body as a city, bustling with activity.

Cells are the workers, and mTOR (mechanistic target of rapamycin) is the city planner, deciding where to focus resources – building new structures, cleaning up waste, or repairing old ones.

As we age, mTOR often prioritizes building (cell growth) over maintenance (cellular repair), leading to “clutter” in our bodies that contributes to aging and disease.

This is where Rapamycin comes in.

It acts like a wise advisor to mTOR, convincing it to slow down unnecessary growth projects and focus on clean up and repair instead.

Specifically, Rapamycin:

Activates cellular recycling (autophagy):

Think of autophagy as the city’s waste management system. Damaged parts of cells are broken down and reused, keeping the system efficient and healthy.

Reduces harmful overgrowth:

Overactive mTOR has been linked to diseases such as cancer, cardiovascular disease, and neurodegenerative conditions like Alzheimer’s. By dialing back excessive growth signals, Rapamycin helps prevent these issues.

Supports stress resilience:

When cells are less focused on growing, they’re better equipped to handle stress, repair damage, and maintain long-term health.