Fasting Insulin

Platelet Count

eGFR (Estimated Glomerular Filtration Rate)

Uric Acid

Monocytes (Absolute)

GGT (Gamma-Glutamyl Transferase)

Copper Serum

MCV (Mean Corpuscular Volume)

Apolipoprotein A1

Glucose

AST (Aspartate Aminotransferase)

DHEA-S (Dehydroepiandrosterone Sulfate)

LDL Particle Size

BUN/Creatinine Ratio

Homocysteine

Lymphocytes (Absolute)

HS-CRP (High-Sensitivity C-Reactive Protein)

RBC (Red Blood Cell Count)

Phosphorous

Total Cholesterol

UIBC (Unsaturated Iron Binding Capacity)

Free T3 (Triiodothyronine)

Neutrophils (Absolute)

Total Testosterone

Hemoglobin A1C

Reverse T3 (rT3)

LDL Particle Number

Sed Rate (Erythrocyte Sedimentation Rate)

IL-6 (Interleukin-6)

ApoA/ApoB Ratio

Immature Granulocytes

Hematocrit

25(OH)D (25-Hydroxyvitamin D)

MCH (Mean Corpuscular Hemoglobin)

DHA (Docosahexaenoic Acid)

Serum Cortisol

Iron Saturation

TIBC (Total Iron Binding Capacity)

Albumin

Alkaline Phosphatase (ALP)

Discover the importance of BUN (Blood Urea Nitrogen) as a crucial biomarker for assessing kidney function and overall longevity. Understand its role in health and aging.

BUN (Blood Urea Nitrogen)

Blood Urea Nitrogen (BUN) is a biomarker commonly used to assess kidney function and overall health. Elevated levels of BUN may indicate kidney impairment, dehydration, or high protein intake, while low levels could be a sign of liver disease or malnutrition. As a longevity expert, monitoring BUN levels can provide valuable insight into an individual’s risk for age-related diseases and overall longevity. Maintaining optimal BUN levels through a balanced diet, hydration, and regular physical activity is essential for promoting healthy aging and preventing age-related decline in kidney function. Regularly monitoring BUN levels can help individuals make informed decisions to support their longevity and well-being.

Biomarker Explained

Blood Urea Nitrogen (BUN) is a crucial biomarker often utilized in longevity research to evaluate an individual’s risk for age-related diseases and overall lifespan. Elevated levels of BUN may indicate compromised kidney function, dehydration, or excessive protein consumption. On the other hand, low levels of BUN could signal liver disease or malnutrition. By monitoring BUN levels, individuals can gain valuable insights into their kidney health and make informed decisions to support their longevity and well-being. Maintaining optimal BUN levels is essential for promoting healthy aging and preventing age-related decline in kidney function. This can be achieved through a balanced diet, adequate hydration, and regular physical activity. Monitoring BUN levels regularly can help individuals understand their risk for age-related diseases and implement necessary lifestyle changes to support their overall longevity. With proper management of BUN levels, individuals can proactively address potential health issues and strive for a longer, healthier lifespan.

Keywords:

Blood Urea Nitrogen, BUN, Biomarker, Longevity, Age-related diseases, Kidney health, Lifestyle changes

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How does Rapaymcin work?

Rapamycin slows aging by targeting the mTOR pathway, shifting the body’s focus from growth to repair. It promotes cellular recycling, reduces overgrowth linked to disease, and enhances resilience to stress.

Imagine your body as a city, bustling with activity.

Cells are the workers, and mTOR (mechanistic target of rapamycin) is the city planner, deciding where to focus resources – building new structures, cleaning up waste, or repairing old ones.

As we age, mTOR often prioritizes building (cell growth) over maintenance (cellular repair), leading to “clutter” in our bodies that contributes to aging and disease.

This is where Rapamycin comes in.

It acts like a wise advisor to mTOR, convincing it to slow down unnecessary growth projects and focus on clean up and repair instead.

Specifically, Rapamycin:

Activates cellular recycling (autophagy):

Think of autophagy as the city’s waste management system. Damaged parts of cells are broken down and reused, keeping the system efficient and healthy.

Reduces harmful overgrowth:

Overactive mTOR has been linked to diseases such as cancer, cardiovascular disease, and neurodegenerative conditions like Alzheimer’s. By dialing back excessive growth signals, Rapamycin helps prevent these issues.

Supports stress resilience:

When cells are less focused on growing, they’re better equipped to handle stress, repair damage, and maintain long-term health.