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Reverse T3 (rT3)

LDL Particle Size

Total Protein

Free T3 (Triiodothyronine)

Hematocrit

Fibrinogen

Eosinophils (Absolute)

HS-CRP (High-Sensitivity C-Reactive Protein)

RDW (Red Cell Distribution Width)

Hemoglobin A1C

SHBG (Sex Hormone Binding Globulin)

Bicarbonate

BUN (Blood Urea Nitrogen)

RBC (Red Blood Cell Count)

Platelet Count

Serum Iron

Lymphocytes (Absolute)

Lactic Acid

MCV (Mean Corpuscular Volume)

Uric Acid

Serum Cortisol

LDL Particle Number

MCH (Mean Corpuscular Hemoglobin)

Hemoglobin

Copper Serum

Homocysteine

IL-6 (Interleukin-6)

Fasting Insulin

eGFR (Estimated Glomerular Filtration Rate)

Cystatin C

Calcium

HOMA-IR (Homeostatic Model Assessment of Insulin Resistance)

BUN/Creatinine Ratio

IGF-1 (Insulin-Like Growth Factor 1)

Sodium

Potassium

LDL Cholesterol (calculated)

Chloride

GGT (Gamma-Glutamyl Transferase)

25(OH)D (25-Hydroxyvitamin D)
Discover the importance of SHBG (Sex Hormone Binding Globulin) as a biomarker for longevity and overall health. Learn about its role and impact on aging.

SHBG (Sex Hormone Binding Globulin)

BioMarkers for Longevity

SHBG (Sex Hormone Binding Globulin) is a crucial biomarker for longevity. As a longevity expert, I stress the importance of monitoring SHBG levels, as it plays a significant role in hormone regulation, particularly in relation to sex hormones such as testosterone and estrogen. Lower levels of SHBG have been linked to an increased risk of chronic diseases and mortality, making it a valuable marker for assessing longevity. Monitoring and optimizing SHBG levels through lifestyle modifications and medical interventions can potentially contribute to extending lifespan and promoting overall health and well-being. Therefore, understanding and managing SHBG levels is essential for those aiming to maximize their longevity.

Biomarker Explained

Sex Hormone Binding Globulin (SHBG) is an important biomarker for assessing longevity. This protein is crucial for regulating sex hormones like testosterone and estrogen, and lower levels of SHBG have been linked to a higher risk of chronic diseases and mortality. As a longevity expert, it is essential to monitor and optimize SHBG levels through lifestyle modifications and medical interventions in order to potentially extend lifespan and promote overall health and well-being. By understanding and managing SHBG levels, individuals can work towards maximizing their longevity and reducing their risk of age-related diseases. It is recommended to regularly monitor SHBG levels and consult with healthcare professionals to develop a personalized approach to optimizing this biomarker for longevity purposes.

Keywords:

Sex Hormone Binding Globulin, SHBG, longevity, biomarker, testosterone, estrogen, chronic diseases, mortality, lifestyle modifications, medical interventions, lifespan, health, well-being, age-related diseases, healthcare professionals, personalized approach, optimizing biomarker

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Longevity Direct logo in color – promoting personalized longevity insights and AI-driven health optimization

Rapamycin

Metformin

GLP-1

General Longevity
Heart Health
Weight Management
Glucose Control
Cognitive Function
Diabetes Prevention
Mood Support
Energy & Fatigue
Autoimmune Support
Blood Pressure
Chronic Pain & Arthritis
Aging Skin
Men’s Aging
Women’s Aging

Longevity Library
About

get Started
Client portal

Contact

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How does Rapaymcin work?

Rapamycin slows aging by targeting the mTOR pathway, shifting the body’s focus from growth to repair. It promotes cellular recycling, reduces overgrowth linked to disease, and enhances resilience to stress.

Imagine your body as a city, bustling with activity.

Cells are the workers, and mTOR (mechanistic target of rapamycin) is the city planner, deciding where to focus resources – building new structures, cleaning up waste, or repairing old ones.

As we age, mTOR often prioritizes building (cell growth) over maintenance (cellular repair), leading to “clutter” in our bodies that contributes to aging and disease.

This is where Rapamycin comes in.

It acts like a wise advisor to mTOR, convincing it to slow down unnecessary growth projects and focus on clean up and repair instead.

Specifically, Rapamycin:

Activates cellular recycling (autophagy):

Think of autophagy as the city’s waste management system. Damaged parts of cells are broken down and reused, keeping the system efficient and healthy.

Reduces harmful overgrowth:

Overactive mTOR has been linked to diseases such as cancer, cardiovascular disease, and neurodegenerative conditions like Alzheimer’s. By dialing back excessive growth signals, Rapamycin helps prevent these issues.

Supports stress resilience:

When cells are less focused on growing, they’re better equipped to handle stress, repair damage, and maintain long-term health.