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Personalized Rapamycin
Starting at $83/mo
(27 reviews)
A clinician-guided longevity protocol focused on resilience, recovery, and long-term healthspan. An effective, extended-release treatment plan with optimization and monitoring throughout.
AS FEATURED IN
Personalized Rapamycin to target the root mechanisms of aging
- Weekly tablet with personalized titration
- Clinician-guided longevity protocol
- Comprehensive labs & monitoring
- Cancel anytime
Quarterly
most popular
$100/mo.
save 20%
Bi-Annually
recommended protocol
$83.16/mo.
save 33%
Join over 10,000+ people
Rapamycin
Prescription rapamycin therapy personalized for your cellular aging and longevity.
50+ Longevity Biomarkers
Comprehensive Metabolic Panel (CMP) • Complete Blood Count (CBC) • Lipid Panel • hsCRP • Hemoglobin A1c
blēo Wearable
The blēo ring combines elegant form with medical-grade sensors.
The Longevity AI
Your all-in-one AI coach to track your progress in real-time.
Transform your longevity journey with Rapamycin
It takes more than medication alone. Achieving lasting longevity is deeply rewarding but requires commitment. That's why we're dedicated to providing the complete range of science-backed pathways you need to unlock your longevity.
STEP 1Find your solution
Ready to take on time itself? Start by exploring our clinically validated treatments, tailored for your longevity.
Science-Backed
How Rapamycin works
Rapamycin operates through four distinct biological mechanisms, each targeting a fundamental aspect of cellular aging and immune regulation.
Inhibits the mTOR Growth Pathway
Rapamycin forms a complex with FKBP12 that directly inhibits mTORC1, a master regulator of cell growth and proliferation. This blocks the G1 to S phase transition, controlling cellular expansion and metabolism.
Suppresses Protein Synthesis
By inhibiting mTORC1, rapamycin blocks the phosphorylation of S6K1 and 4E-BP1, critical regulators of protein translation. This reduces synthesis of proteins required for cell growth, slowing cellular machinery that drives proliferation.
Activates Cellular Autophagy
Rapamycin promotes autophagy, a cellular recycling process where damaged proteins and organelles are broken down and removed. This housekeeping mechanism helps maintain cellular quality and extends cellular lifespan.
Modulates Immune Cell Activity
Rapamycin selectively inhibits T-cell proliferation while expanding regulatory T cells (Tregs). This dual action creates a more balanced immune state without global immunosuppression.
Inhibits the mTOR Growth Pathway
Rapamycin forms a complex with FKBP12 that directly inhibits mTORC1, a master regulator of cell growth and proliferation. This blocks the G1 to S phase transition, controlling cellular expansion and metabolism.
Suppresses Protein Synthesis
By inhibiting mTORC1, rapamycin blocks the phosphorylation of S6K1 and 4E-BP1, critical regulators of protein translation. This reduces synthesis of proteins required for cell growth, slowing cellular machinery that drives proliferation.
Activates Cellular Autophagy
Rapamycin promotes autophagy, a cellular recycling process where damaged proteins and organelles are broken down and removed. This housekeeping mechanism helps maintain cellular quality and extends cellular lifespan.
Modulates Immune Cell Activity
Rapamycin selectively inhibits T-cell proliferation while expanding regulatory T cells (Tregs). This dual action creates a more balanced immune state without global immunosuppression.
Testimonials
What our members say
Discover how our members have transformed their health and vitality.
"After just a few months, I feel more energetic and focused than I have in years. The personalized plan is truly making a difference."
"The data-driven approach gave me incredible insights into my health. It's empowering to see my biomarkers improve over time."
"I was skeptical at first, but the results speak for themselves. My sleep has improved, and I've noticed a significant boost in my overall well-being."
"After just a few months, I feel more energetic and focused than I have in years. The personalized plan is truly making a difference."
"The data-driven approach gave me incredible insights into my health. It's empowering to see my biomarkers improve over time."
"I was skeptical at first, but the results speak for themselves. My sleep has improved, and I've noticed a significant boost in my overall well-being."
"The clinical team is top-notch. They explained everything clearly and are always available to answer my questions. I feel like I'm in great hands."
"Integrating the biometric wearable was seamless. It's fascinating to see how my daily habits directly impact my long-term health metrics."
"This program is an investment in my future self. The proactive approach to health is a game-changer."
"The clinical team is top-notch. They explained everything clearly and are always available to answer my questions. I feel like I'm in great hands."
"Integrating the biometric wearable was seamless. It's fascinating to see how my daily habits directly impact my long-term health metrics."
"This program is an investment in my future self. The proactive approach to health is a game-changer."
"My cognitive function has noticeably improved. I feel sharper at work and more present in my daily life."
"The convenience of having everything managed online, from consultations to medication delivery, is incredible."
"Finally, a healthcare company that's focused on optimizing healthspan, not just treating sickness. I highly recommend it."
"My cognitive function has noticeably improved. I feel sharper at work and more present in my daily life."
"The convenience of having everything managed online, from consultations to medication delivery, is incredible."
"Finally, a healthcare company that's focused on optimizing healthspan, not just treating sickness. I highly recommend it."
Research Uncovered
Backed by Science
Explore the clinical research and scientific evidence that validate the benefits for health and longevity.
Clinically Proven Lifespan Extension
Research demonstrates up to 14% lifespan extension when started mid-life—the equivalent of gaining over a decade of healthy years.
Kaeberlein, Geroscience, 2019It's Never Too Late to Start
Even when started at age 50+ equivalent, rapamycin extended healthy lifespan by 9–14% across genders in controlled studies.
Harrison et al., Nature, 2009Backed by Decades of Research
Over 20 years of peer-reviewed studies consistently demonstrate rapamycin's longevity potential.
Doni et al., JPM, 2023Longevity Without Restriction
Achieve lifespan benefits comparable to caloric restriction—without changing what you eat.
Kaeberlein, Geroscience, 2019Ready for longevity?
* Rapamycin is not FDA-approved for the treatment of longevity or anti-aging purposes. Learn more about 'off-label' uses.
* Prescription products are subject to healthcare provider approval and require an online consultation with a healthcare provider after checkout who will determine if a prescription is appropriate. Take the medication as directed by your protocols.
* Common side effects of Rapamycin include mouth sores, diarrhea, joint pain, acne, headache, or increased risk of infection. Do not take Rapamycin if you are allergic to it, have liver disease, or have a history of lung or breathing problems.
* Call your doctor immediately if you have symptoms of an allergic reaction such as rash, itching, swelling, severe dizziness, trouble breathing, or symptoms of serious infections.
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