Up to 45% of adults experience regular fatigue, with lifestyle factors such as poor sleep, stress, and lack of physical activity being the main contributors.
Addressing fatigue early can improve quality of life and overall longevity.
Sustained energy levels aren’t just about getting through the day – they’re essential for long-term health and vitality.
More energy means staying focused and productive throughout the day, improving both physical and mental performance.
Managing fatigue early helps prevent the onset of chronic fatigue syndrome, which can affect long-term health and well-being.
Sustained energy levels promote better mental clarity and cognitive function, keeping your brain sharp and your mood balanced.
Make water your beverage of choice
Plan consistent, healthy meals
Avoid sugary and high-carb foods and drinks
Get sufficient rest every night
Consider Acarbose, a starchy carb blocker, to decrease spikes
Use a Continuous Glucose Monitor (CGM) to understand your current levels
Switch to balanced, low-carb meals
Establish an exercise routine
Minimize stress levels
Consider Metformin to lower blood sugar levels
Use a CGM periodically over any 14-day period
Understand how your habits affect your blood sugar
Measure efficacy of diet, exercise, and lifestyle changes
Monitor your body’s response to treatments
Analyze, adjust, and repeat
Use a Continuous Glucose Monitor (CGM) to understand your current levels
Switch to balanced, low-carb meals
Establish an exercise routine
Minimize stress levels
Consider Metformin to lower blood sugar levels
Studies indicate that metformin can extend lifespan by improving metabolic efficiency and delaying the onset of metabolic diseases. Metformin activates the AMPK pathway, which is pivotal in regulating metabolism and cellular energy homeostasis.
Talk to your healthcare provider to see if a glucose management plan is right for you. Prescription products require an online consultation with a physician who will determine if a prescription is appropriate. See product page for important safety information. Benefits outlined on longevity.direct are based on 3rd party studies.
Note: The above statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
Longevity Direct is an element within Longr’s Longevity OS, a platform dedicated to extending access to longevity.
© 2025 Longr Holdings Inc.
Rapamycin slows aging by targeting the mTOR pathway, shifting the body’s focus from growth to repair. It promotes cellular recycling, reduces overgrowth linked to disease, and enhances resilience to stress.
Imagine your body as a city, bustling with activity.
Cells are the workers, and mTOR (mechanistic target of rapamycin) is the city planner, deciding where to focus resources – building new structures, cleaning up waste, or repairing old ones.
As we age, mTOR often prioritizes building (cell growth) over maintenance (cellular repair), leading to “clutter” in our bodies that contributes to aging and disease.
This is where Rapamycin comes in.
It acts like a wise advisor to mTOR, convincing it to slow down unnecessary growth projects and focus on clean up and repair instead.
Specifically, Rapamycin:
Activates cellular recycling (autophagy):
Think of autophagy as the city’s waste management system. Damaged parts of cells are broken down and reused, keeping the system efficient and healthy.
Reduces harmful overgrowth:
Overactive mTOR has been linked to diseases such as cancer, cardiovascular disease, and neurodegenerative conditions like Alzheimer’s. By dialing back excessive growth signals, Rapamycin helps prevent these issues.
Supports stress resilience:
When cells are less focused on growing, they’re better equipped to handle stress, repair damage, and maintain long-term health.