Fasting Insulin

Free T4 (Thyroxine)

Basophils (Absolute)

A/G Ratio (Albumin/Globulin Ratio)

WBC (White Blood Cell Count)

Bicarbonate

MCH (Mean Corpuscular Hemoglobin)

EPA (Eicosapentaenoic Acid)

Vitamin A (Retinol)

Iron Saturation

LDL Particle Size

Reverse T3 (rT3)

TNF-α (Tumor Necrosis Factor-alpha)

HOMA-IR (Homeostatic Model Assessment of Insulin Resistance)

LDL Cholesterol (calculated)

UIBC (Unsaturated Iron Binding Capacity)

Homocysteine

LDH (Lactate Dehydrogenase)

MCV (Mean Corpuscular Volume)

Neutrophils (Absolute)

AST (Aspartate Aminotransferase)

TPO Ab (Thyroid Peroxidase Antibodies)

Tg Ab (Thyroglobulin Antibodies)

Phosphorous

Ceruloplasmin

Bilirubin (Total and Direct)

IGF-1 (Insulin-Like Growth Factor 1)

ANA (Antinuclear Antibody)

Total Protein

Alkaline Phosphatase (ALP)

25(OH)D (25-Hydroxyvitamin D)

Chloride

Triglycerides

Free T3 (Triiodothyronine)

ApoA/ApoB Ratio

SHBG (Sex Hormone Binding Globulin)

Calcium

Glucose

GGT (Gamma-Glutamyl Transferase)

Creatinine

Discover the importance of TPO Ab (Thyroid Peroxidase Antibodies) as a biomarker for longevity. Learn how monitoring this marker can impact overall health.

TPO Ab (Thyroid Peroxidase Antibodies)

TPO Ab (Thyroid Peroxidase Antibodies) are biomarkers commonly used in longevity research and assessment. These antibodies are associated with autoimmune thyroid disorders, which can impact overall health and longevity. Elevated levels of TPO Ab may indicate an increased risk of thyroid-related conditions, such as hypothyroidism or Hashimoto’s disease, which can contribute to a variety of health issues and affect longevity. Monitoring TPO Ab levels can provide valuable insights into individual health and potential longevity considerations. As part of a comprehensive biomarker profile, TPO Ab can help inform personalized strategies for optimizing health and promoting longevity.

Biomarker Explained

TPO Ab, or Thyroid Peroxidase Antibodies, is a biomarker commonly utilized in longevity research and assessment. Elevated levels of TPO Ab are associated with autoimmune thyroid disorders, which can have a significant impact on overall health and longevity. These elevated levels may indicate an increased risk of thyroid-related conditions, such as hypothyroidism or Hashimoto’s disease, which in turn can lead to a variety of health issues and potentially affect longevity. Therefore, monitoring TPO Ab levels can provide valuable insights into an individual’s health and potential longevity considerations. As part of a comprehensive biomarker profile, TPO Ab can help inform personalized strategies for optimizing health and promoting longevity. By interpreting TPO Ab levels, individuals and healthcare professionals can identify potential risks and tailor interventions to mitigate them, ultimately working towards improving overall health and extending longevity.

Keywords:

TPO Ab, Thyroid Peroxidase Antibodies, biomarker, longevity research, autoimmune thyroid disorders, hypothyroidism, Hashimoto’s disease

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How does Rapaymcin work?

Rapamycin slows aging by targeting the mTOR pathway, shifting the body’s focus from growth to repair. It promotes cellular recycling, reduces overgrowth linked to disease, and enhances resilience to stress.

Imagine your body as a city, bustling with activity.

Cells are the workers, and mTOR (mechanistic target of rapamycin) is the city planner, deciding where to focus resources – building new structures, cleaning up waste, or repairing old ones.

As we age, mTOR often prioritizes building (cell growth) over maintenance (cellular repair), leading to “clutter” in our bodies that contributes to aging and disease.

This is where Rapamycin comes in.

It acts like a wise advisor to mTOR, convincing it to slow down unnecessary growth projects and focus on clean up and repair instead.

Specifically, Rapamycin:

Activates cellular recycling (autophagy):

Think of autophagy as the city’s waste management system. Damaged parts of cells are broken down and reused, keeping the system efficient and healthy.

Reduces harmful overgrowth:

Overactive mTOR has been linked to diseases such as cancer, cardiovascular disease, and neurodegenerative conditions like Alzheimer’s. By dialing back excessive growth signals, Rapamycin helps prevent these issues.

Supports stress resilience:

When cells are less focused on growing, they’re better equipped to handle stress, repair damage, and maintain long-term health.