Bicarbonate

TIBC (Total Iron Binding Capacity)

25(OH)D (25-Hydroxyvitamin D)

LDL Particle Number

Total Cholesterol

Vitamin A (Retinol)

Platelet Count

LDL Cholesterol (calculated)

Copper Serum

Fasting Insulin

Ceruloplasmin

Hemoglobin A1C

WBC (White Blood Cell Count)

TSH (Thyroid Stimulating Hormone)

DHA (Docosahexaenoic Acid)

Serum Cortisol

Apolipoprotein A1

Chloride

RDW (Red Cell Distribution Width)

RBC (Red Blood Cell Count)

TNF-α (Tumor Necrosis Factor-alpha)

Fibrinogen

A/G Ratio (Albumin/Globulin Ratio)

TPO Ab (Thyroid Peroxidase Antibodies)

IL-6 (Interleukin-6)

BUN (Blood Urea Nitrogen)

Eosinophils (Absolute)

Albumin

Total Protein

Lymphocytes (Absolute)

BUN/Creatinine Ratio

Tg Ab (Thyroglobulin Antibodies)

VLDL Cholesterol (calculated)

Alkaline Phosphatase (ALP)

Calcium

Serum Iron

Sed Rate (Erythrocyte Sedimentation Rate)

SHBG (Sex Hormone Binding Globulin)

Hemoglobin

HS-CRP (High-Sensitivity C-Reactive Protein)

Discover the importance of BUN (Blood Urea Nitrogen) as a crucial biomarker for assessing kidney function and overall longevity. Understand its role in health and aging.

BUN (Blood Urea Nitrogen)

Blood Urea Nitrogen (BUN) is a biomarker commonly used to assess kidney function and overall health. Elevated levels of BUN may indicate kidney impairment, dehydration, or high protein intake, while low levels could be a sign of liver disease or malnutrition. As a longevity expert, monitoring BUN levels can provide valuable insight into an individual’s risk for age-related diseases and overall longevity. Maintaining optimal BUN levels through a balanced diet, hydration, and regular physical activity is essential for promoting healthy aging and preventing age-related decline in kidney function. Regularly monitoring BUN levels can help individuals make informed decisions to support their longevity and well-being.

Biomarker Explained

Blood Urea Nitrogen (BUN) is a crucial biomarker often utilized in longevity research to evaluate an individual’s risk for age-related diseases and overall lifespan. Elevated levels of BUN may indicate compromised kidney function, dehydration, or excessive protein consumption. On the other hand, low levels of BUN could signal liver disease or malnutrition. By monitoring BUN levels, individuals can gain valuable insights into their kidney health and make informed decisions to support their longevity and well-being. Maintaining optimal BUN levels is essential for promoting healthy aging and preventing age-related decline in kidney function. This can be achieved through a balanced diet, adequate hydration, and regular physical activity. Monitoring BUN levels regularly can help individuals understand their risk for age-related diseases and implement necessary lifestyle changes to support their overall longevity. With proper management of BUN levels, individuals can proactively address potential health issues and strive for a longer, healthier lifespan.

Keywords:

Blood Urea Nitrogen, BUN, Biomarker, Longevity, Age-related diseases, Kidney health, Lifestyle changes

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How does Rapaymcin work?

Rapamycin slows aging by targeting the mTOR pathway, shifting the body’s focus from growth to repair. It promotes cellular recycling, reduces overgrowth linked to disease, and enhances resilience to stress.

Imagine your body as a city, bustling with activity.

Cells are the workers, and mTOR (mechanistic target of rapamycin) is the city planner, deciding where to focus resources – building new structures, cleaning up waste, or repairing old ones.

As we age, mTOR often prioritizes building (cell growth) over maintenance (cellular repair), leading to “clutter” in our bodies that contributes to aging and disease.

This is where Rapamycin comes in.

It acts like a wise advisor to mTOR, convincing it to slow down unnecessary growth projects and focus on clean up and repair instead.

Specifically, Rapamycin:

Activates cellular recycling (autophagy):

Think of autophagy as the city’s waste management system. Damaged parts of cells are broken down and reused, keeping the system efficient and healthy.

Reduces harmful overgrowth:

Overactive mTOR has been linked to diseases such as cancer, cardiovascular disease, and neurodegenerative conditions like Alzheimer’s. By dialing back excessive growth signals, Rapamycin helps prevent these issues.

Supports stress resilience:

When cells are less focused on growing, they’re better equipped to handle stress, repair damage, and maintain long-term health.