Glucose

HS-CRP (High-Sensitivity C-Reactive Protein)

Reverse T3 (rT3)

Fibrinogen

Homocysteine

Free T4 (Thyroxine)

BUN (Blood Urea Nitrogen)

Copper Serum

Phosphorous

Iron Saturation

HOMA-IR (Homeostatic Model Assessment of Insulin Resistance)

Platelet Count

Sed Rate (Erythrocyte Sedimentation Rate)

Apolipoprotein A1

Serum Iron

TPO Ab (Thyroid Peroxidase Antibodies)

ALT (Alanine Aminotransferase)

NRBC (Nucleated Red Blood Cells)

DHEA-S (Dehydroepiandrosterone Sulfate)

Sodium

MCH (Mean Corpuscular Hemoglobin)

Free Testosterone

Ceruloplasmin

ApoA/ApoB Ratio

Total Testosterone

Immature Granulocytes

TNF-α (Tumor Necrosis Factor-alpha)

Potassium

LDL Particle Number

SHBG (Sex Hormone Binding Globulin)

IGF-1 (Insulin-Like Growth Factor 1)

Total Cholesterol

Bicarbonate

Lymphocytes (Absolute)

MCHC (Mean Corpuscular Hemoglobin Concentration)

Hematocrit

Eosinophils (Absolute)

LDH (Lactate Dehydrogenase)

TIBC (Total Iron Binding Capacity)

A/G Ratio (Albumin/Globulin Ratio)

Apolipoprotein A1 is a biomarker used in longevity research to assess cardiovascular health and predict risk of age-related diseases.

Apolipoprotein A1

Apolipoprotein A1 is a critical biomarker used in assessing the risk of cardiovascular diseases and overall longevity. It is a major component of high-density lipoprotein (HDL) particles and plays a central role in the reverse cholesterol transport pathway. Higher levels of Apolipoprotein A1 are associated with a reduced risk of developing heart diseases and are considered a favorable biomarker for longevity. Studies have shown that individuals with higher Apolipoprotein A1 levels tend to live longer and have better cardiovascular health. Thus, monitoring Apolipoprotein A1 levels can provide valuable insights into an individual’s potential for living a longer and healthier life.

Biomarker Explained

Apolipoprotein A1 is a crucial biomarker used in assessing an individual’s potential for longevity. This biomarker is a major component of high-density lipoprotein (HDL) particles and plays a central role in the reverse cholesterol transport pathway. Higher levels of Apolipoprotein A1 are associated with a reduced risk of developing heart diseases, making it a favorable biomarker for longevity. Studies have demonstrated that individuals with higher Apolipoprotein A1 levels tend to live longer and have better cardiovascular health. Therefore, monitoring Apolipoprotein A1 levels can provide valuable insights into an individual’s potential for living a longer and healthier life. Assessing the levels of Apolipoprotein A1 in an individual’s blood can help predict their risk of cardiovascular diseases and overall longevity. It is essential to consider this biomarker in combination with other relevant factors to gain a comprehensive understanding of an individual’s potential for longevity.

Keywords:

Apolipoprotein A1, longevity, biomarker, high-density lipoprotein (HDL), reverse cholesterol transport, cardiovascular health, potential for living longer

How does Rapaymcin work?

Rapamycin slows aging by targeting the mTOR pathway, shifting the body’s focus from growth to repair. It promotes cellular recycling, reduces overgrowth linked to disease, and enhances resilience to stress.

Imagine your body as a city, bustling with activity.

Cells are the workers, and mTOR (mechanistic target of rapamycin) is the city planner, deciding where to focus resources – building new structures, cleaning up waste, or repairing old ones.

As we age, mTOR often prioritizes building (cell growth) over maintenance (cellular repair), leading to “clutter” in our bodies that contributes to aging and disease.

This is where Rapamycin comes in.

It acts like a wise advisor to mTOR, convincing it to slow down unnecessary growth projects and focus on cleanup and repair instead.

Specifically, Rapamycin:

  • Activates cellular recycling (autophagy):
    Think of autophagy as the city’s waste management system. Damaged parts of cells are broken down and reused, keeping the system efficient and healthy.

  • Reduces harmful overgrowth:
    Overactive mTOR has been linked to diseases such as cancer, cardiovascular disease, and neurodegenerative conditions like Alzheimer’s. By dialing back excessive growth signals, Rapamycin helps prevent these issues.

  • Supports stress resilience:
    When cells are less focused on growing, they’re better equipped to handle stress, repair damage, and maintain long-term health.