Sed Rate (Erythrocyte Sedimentation Rate)

Free T4 (Thyroxine)

Uric Acid

Copper Serum

BUN/Creatinine Ratio

Cystatin C

eGFR (Estimated Glomerular Filtration Rate)

Creatinine

ANA (Antinuclear Antibody)

ALT (Alanine Aminotransferase)

Potassium

TPO Ab (Thyroid Peroxidase Antibodies)

Lymphocytes (Absolute)

WBC (White Blood Cell Count)

Albumin

Immature Granulocytes

Fasting Insulin

Hemoglobin A1C

IL-6 (Interleukin-6)

Phosphorous

Apolipoprotein B

Calcium

Hematocrit

ApoA/ApoB Ratio

RBC (Red Blood Cell Count)

EPA (Eicosapentaenoic Acid)

Vitamin A (Retinol)

Sodium

A/G Ratio (Albumin/Globulin Ratio)

25(OH)D (25-Hydroxyvitamin D)

IGF-1 (Insulin-Like Growth Factor 1)

GGT (Gamma-Glutamyl Transferase)

Serum Cortisol

Alkaline Phosphatase (ALP)

TSH (Thyroid Stimulating Hormone)

Total Protein

BUN (Blood Urea Nitrogen)

LDL Cholesterol (calculated)

Lipoprotein(a) [Lp(a)]

LDL Particle Number

"VLDL Cholesterol, a calculated biomarker, is used by longevity experts to assess cardiovascular health and disease risk for promoting a longer, healthier life."

VLDL Cholesterol (calculated)

VLDL cholesterol, or very low-density lipoprotein cholesterol, is a type of lipid particle in the blood that is often associated with cardiovascular disease risk. In the context of longevity, monitoring and managing VLDL cholesterol levels is important as it is a key biomarker for assessing heart health and overall longevity. High levels of VLDL cholesterol are linked to an increased risk of atherosclerosis, heart attack, and stroke, all of which can significantly impact life expectancy. By keeping VLDL cholesterol levels within a healthy range through lifestyle modifications and, if necessary, medication, individuals can help promote their longevity and reduce the risk of cardiovascular disease.

Biomarker Explained

VLDL cholesterol, or very low-density lipoprotein cholesterol, is a crucial biomarker for assessing longevity. This lipid particle in the blood is closely associated with cardiovascular disease risk, making it an important factor in determining overall health and lifespan. High levels of VLDL cholesterol are linked to an increased risk of atherosclerosis, heart attack, and stroke, all of which can significantly impact life expectancy. Therefore, monitoring and managing VLDL cholesterol levels is essential for promoting longevity. Interpreting VLDL cholesterol levels involves keeping them within a healthy range through lifestyle modifications such as a balanced diet, regular exercise, and weight management, as well as, if necessary, medication. Maintaining healthy VLDL cholesterol levels is crucial for reducing the risk of cardiovascular disease and promoting longevity. Consequently, individuals should work with healthcare professionals to monitor and manage their VLDL cholesterol levels in order to optimize their heart health and overall longevity.

Keywords:

VLDL cholesterol, very low-density lipoprotein cholesterol, cardiovascular disease risk, atherosclerosis, longevity, lifestyle modifications, medication

How does Rapaymcin work?

Rapamycin slows aging by targeting the mTOR pathway, shifting the body’s focus from growth to repair. It promotes cellular recycling, reduces overgrowth linked to disease, and enhances resilience to stress.

Imagine your body as a city, bustling with activity.

Cells are the workers, and mTOR (mechanistic target of rapamycin) is the city planner, deciding where to focus resources – building new structures, cleaning up waste, or repairing old ones.

As we age, mTOR often prioritizes building (cell growth) over maintenance (cellular repair), leading to “clutter” in our bodies that contributes to aging and disease.

This is where Rapamycin comes in.

It acts like a wise advisor to mTOR, convincing it to slow down unnecessary growth projects and focus on cleanup and repair instead.

Specifically, Rapamycin:

  • Activates cellular recycling (autophagy):
    Think of autophagy as the city’s waste management system. Damaged parts of cells are broken down and reused, keeping the system efficient and healthy.

  • Reduces harmful overgrowth:
    Overactive mTOR has been linked to diseases such as cancer, cardiovascular disease, and neurodegenerative conditions like Alzheimer’s. By dialing back excessive growth signals, Rapamycin helps prevent these issues.

  • Supports stress resilience:
    When cells are less focused on growing, they’re better equipped to handle stress, repair damage, and maintain long-term health.