Interleukin-6 (IL-6) is a biomarker that has been associated with longevity and healthy aging. It is a proinflammatory cytokine that plays a pivotal role in the immune response and inflammation. Elevated levels of IL-6 have been linked to chronic age-related diseases, such as cardiovascular disease, diabetes, and certain types of cancer. Additionally, high IL-6 levels have been shown to be a predictor of mortality in older adults. Monitoring IL-6 levels may provide valuable insights into an individual’s overall health and potential risk for age-related diseases. Understanding and managing IL-6 levels could be a crucial aspect of promoting longevity and healthy aging.