Alkaline Phosphatase (ALP)

Albumin

Bilirubin (Total and Direct)

HS-CRP (High-Sensitivity C-Reactive Protein)

Total Protein

BUN (Blood Urea Nitrogen)

Apolipoprotein B

Sodium

Serum Cortisol

NRBC (Nucleated Red Blood Cells)

TNF-α (Tumor Necrosis Factor-alpha)

ApoA/ApoB Ratio

Creatinine

HDL Cholesterol

Vitamin A (Retinol)

LDH (Lactate Dehydrogenase)

ANA (Antinuclear Antibody)

VLDL Cholesterol (calculated)

Sed Rate (Erythrocyte Sedimentation Rate)

Homocysteine

ALT (Alanine Aminotransferase)

Fibrinogen

Lymphocytes (Absolute)

Phosphorous

MCHC (Mean Corpuscular Hemoglobin Concentration)

SHBG (Sex Hormone Binding Globulin)

TPO Ab (Thyroid Peroxidase Antibodies)

IL-6 (Interleukin-6)

IGF-1 (Insulin-Like Growth Factor 1)

GGT (Gamma-Glutamyl Transferase)

Lipoprotein(a) [Lp(a)]

eGFR (Estimated Glomerular Filtration Rate)

Free T4 (Thyroxine)

Glucose

Cystatin C

RBC (Red Blood Cell Count)

EPA (Eicosapentaenoic Acid)

Copper Serum

Platelet Count

Immature Granulocytes

Discover the role of IL-6 as a potential biomarker for longevity. Learn how this pro-inflammatory cytokine can impact aging and overall health.

IL-6 (Interleukin-6)

Interleukin-6 (IL-6) is a biomarker that has been associated with longevity and healthy aging. It is a proinflammatory cytokine that plays a pivotal role in the immune response and inflammation. Elevated levels of IL-6 have been linked to chronic age-related diseases, such as cardiovascular disease, diabetes, and certain types of cancer. Additionally, high IL-6 levels have been shown to be a predictor of mortality in older adults. Monitoring IL-6 levels may provide valuable insights into an individual’s overall health and potential risk for age-related diseases. Understanding and managing IL-6 levels could be a crucial aspect of promoting longevity and healthy aging.

Biomarker Explained

Interleukin-6 (IL-6) is a critical biomarker for longevity and healthy aging. As a proinflammatory cytokine, IL-6 plays a crucial role in the immune response and inflammation. Elevated levels of IL-6 have been strongly linked to chronic age-related diseases such as cardiovascular disease, diabetes, and certain types of cancer. Moreover, high levels of IL-6 have been shown to be a predictor of mortality in older adults. Therefore, monitoring IL-6 levels can provide valuable insights into an individual’s overall health and potential risk for age-related diseases. In order to promote longevity and healthy aging, it is essential to understand and manage IL-6 levels. By doing so, we can potentially mitigate the risk of chronic diseases and promote overall well-being in aging individuals.

Keywords:

IL-6, biomarker, longevity, healthy aging, proinflammatory cytokine, chronic diseases, mortality

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How does Rapaymcin work?

Rapamycin slows aging by targeting the mTOR pathway, shifting the body’s focus from growth to repair. It promotes cellular recycling, reduces overgrowth linked to disease, and enhances resilience to stress.

Imagine your body as a city, bustling with activity.

Cells are the workers, and mTOR (mechanistic target of rapamycin) is the city planner, deciding where to focus resources – building new structures, cleaning up waste, or repairing old ones.

As we age, mTOR often prioritizes building (cell growth) over maintenance (cellular repair), leading to “clutter” in our bodies that contributes to aging and disease.

This is where Rapamycin comes in.

It acts like a wise advisor to mTOR, convincing it to slow down unnecessary growth projects and focus on clean up and repair instead.

Specifically, Rapamycin:

Activates cellular recycling (autophagy):

Think of autophagy as the city’s waste management system. Damaged parts of cells are broken down and reused, keeping the system efficient and healthy.

Reduces harmful overgrowth:

Overactive mTOR has been linked to diseases such as cancer, cardiovascular disease, and neurodegenerative conditions like Alzheimer’s. By dialing back excessive growth signals, Rapamycin helps prevent these issues.

Supports stress resilience:

When cells are less focused on growing, they’re better equipped to handle stress, repair damage, and maintain long-term health.