Creatinine

Alkaline Phosphatase (ALP)

EPA (Eicosapentaenoic Acid)

DHA (Docosahexaenoic Acid)

Fibrinogen

LDL Particle Number

Free T3 (Triiodothyronine)

RBC Magnesium

Serum Cortisol

ALT (Alanine Aminotransferase)

ApoA/ApoB Ratio

Total Protein

Triglycerides

Reverse T3 (rT3)

SHBG (Sex Hormone Binding Globulin)

Bilirubin (Total and Direct)

ANA (Antinuclear Antibody)

Free Testosterone

Hematocrit

Tg Ab (Thyroglobulin Antibodies)

eGFR (Estimated Glomerular Filtration Rate)

Ferritin

Lactic Acid

Serum Iron

Iron Saturation

Total Cholesterol

MCHC (Mean Corpuscular Hemoglobin Concentration)

Copper Serum

HS-CRP (High-Sensitivity C-Reactive Protein)

Hemoglobin A1C

HDL Cholesterol

Sodium

Total Testosterone

Calcium

GGT (Gamma-Glutamyl Transferase)

25(OH)D (25-Hydroxyvitamin D)

Monocytes (Absolute)

LDL Particle Size

Potassium

Homocysteine

Biomarker Vitamin A (Retinol) levels can be important for longevity. Low levels may indicate increased risk of age-related diseases.

Vitamin A (Retinol)

The biomarker Vitamin A (Retinol) plays a pivotal role in assessing longevity. As a fat-soluble vitamin, it serves as a potent antioxidant and immune system booster, combatting oxidative stress and inflammation, both of which are key factors in aging and age-related diseases. Low levels of Vitamin A have been linked to diminished immune function and increased mortality risk, while optimal levels are associated with improved overall health and longevity. Monitoring Vitamin A levels can provide valuable insights into an individual’s cellular health and resilience, offering a valuable tool for assessing and optimizing longevity.

Biomarker Explained

Vitamin A, also known as Retinol, is a crucial biomarker in assessing longevity. As a fat-soluble vitamin, it acts as a powerful antioxidant and immune system enhancer, combating oxidative stress and inflammation – both of which are significant contributors to aging and age-related diseases. Low levels of Vitamin A have been correlated with weakened immune function and an increased risk of mortality, while optimal levels are associated with improved overall health and longevity. Monitoring Vitamin A levels can provide valuable insights into an individual’s cellular health and resilience, offering a valuable tool for assessing and optimizing longevity. It is essential to interpret Vitamin A levels within the context of an individual’s overall health and lifestyle factors, and when combined with other biomarkers, it can offer a comprehensive understanding of an individual’s biological age and potential longevity.

Keywords:

Vitamin A, Retinol, biomarker, longevity, antioxidant, immune system, inflammation

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How does Rapaymcin work?

Rapamycin slows aging by targeting the mTOR pathway, shifting the body’s focus from growth to repair. It promotes cellular recycling, reduces overgrowth linked to disease, and enhances resilience to stress.

Imagine your body as a city, bustling with activity.

Cells are the workers, and mTOR (mechanistic target of rapamycin) is the city planner, deciding where to focus resources – building new structures, cleaning up waste, or repairing old ones.

As we age, mTOR often prioritizes building (cell growth) over maintenance (cellular repair), leading to “clutter” in our bodies that contributes to aging and disease.

This is where Rapamycin comes in.

It acts like a wise advisor to mTOR, convincing it to slow down unnecessary growth projects and focus on clean up and repair instead.

Specifically, Rapamycin:

Activates cellular recycling (autophagy):

Think of autophagy as the city’s waste management system. Damaged parts of cells are broken down and reused, keeping the system efficient and healthy.

Reduces harmful overgrowth:

Overactive mTOR has been linked to diseases such as cancer, cardiovascular disease, and neurodegenerative conditions like Alzheimer’s. By dialing back excessive growth signals, Rapamycin helps prevent these issues.

Supports stress resilience:

When cells are less focused on growing, they’re better equipped to handle stress, repair damage, and maintain long-term health.