Monocytes (Absolute)

Hemoglobin

HOMA-IR (Homeostatic Model Assessment of Insulin Resistance)

Apolipoprotein B

IGF-1 (Insulin-Like Growth Factor 1)

HDL Cholesterol

Fasting Insulin

Fibrinogen

ALT (Alanine Aminotransferase)

Insulin

RBC (Red Blood Cell Count)

TIBC (Total Iron Binding Capacity)

Lymphocytes (Absolute)

Alkaline Phosphatase (ALP)

LDL Particle Number

Chloride

Total Protein

Reverse T3 (rT3)

Neutrophils (Absolute)

Tg Ab (Thyroglobulin Antibodies)

ANA (Antinuclear Antibody)

Free T4 (Thyroxine)

TSH (Thyroid Stimulating Hormone)

Potassium

Bilirubin (Total and Direct)

Apolipoprotein A1

AST (Aspartate Aminotransferase)

RDW (Red Cell Distribution Width)

Ferritin

Glucose

UIBC (Unsaturated Iron Binding Capacity)

Serum Iron

Free T3 (Triiodothyronine)

A/G Ratio (Albumin/Globulin Ratio)

VLDL Cholesterol (calculated)

Calcium

Lactic Acid

RBC Magnesium

SHBG (Sex Hormone Binding Globulin)

Vitamin A (Retinol)

Discover how Nucleated Red Blood Cells (NRBC) are used as a biomarker for longevity. Learn about their role in predicting aging and age-related diseases.

NRBC (Nucleated Red Blood Cells)

Nucleated Red Blood Cells (NRBC) are a promising biomarker for assessing longevity. These cells, which are typically only found in the bone marrow and are not present in the normal circulation of healthy individuals, have been linked to various age-related diseases and conditions. Elevated levels of NRBCs have been associated with increased mortality and a higher risk of developing cardiovascular disease, cancer, and other chronic illnesses. Monitoring NRBC levels can provide valuable insight into the aging process and overall health status, allowing for early intervention and personalized treatment strategies to promote longevity and healthy aging.

Biomarker Explained

Nucleated Red Blood Cells (NRBC) are an important biomarker for assessing longevity. These cells, typically only found in the bone marrow and not in the normal circulation of healthy individuals, have been linked to various age-related diseases and conditions. Elevated levels of NRBCs have been associated with increased mortality and a higher risk of developing cardiovascular disease, cancer, and other chronic illnesses. Monitoring NRBC levels can provide valuable insight into the aging process and overall health status. By evaluating NRBC levels, healthcare professionals can identify individuals who may be at higher risk for age-related diseases and conditions. This allows for early intervention and personalized treatment strategies to promote longevity and healthy aging. When interpreting NRBC levels, it is important to consider the individual’s age, medical history, and other risk factors for age-related diseases. Additionally, trends in NRBC levels over time can provide important information about the progression of aging and potential health outcomes. In summary, NRBCs serve as a promising biomarker for assessing longevity and can provide valuable information for early intervention and personalized treatment strategies to promote healthy aging.

Keywords:

Nucleated Red Blood Cells, NRBC, longevity, biomarker, aging, cardiovascular disease, personalized treatment strategies

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How does Rapaymcin work?

Rapamycin slows aging by targeting the mTOR pathway, shifting the body’s focus from growth to repair. It promotes cellular recycling, reduces overgrowth linked to disease, and enhances resilience to stress.

Imagine your body as a city, bustling with activity.

Cells are the workers, and mTOR (mechanistic target of rapamycin) is the city planner, deciding where to focus resources – building new structures, cleaning up waste, or repairing old ones.

As we age, mTOR often prioritizes building (cell growth) over maintenance (cellular repair), leading to “clutter” in our bodies that contributes to aging and disease.

This is where Rapamycin comes in.

It acts like a wise advisor to mTOR, convincing it to slow down unnecessary growth projects and focus on clean up and repair instead.

Specifically, Rapamycin:

Activates cellular recycling (autophagy):

Think of autophagy as the city’s waste management system. Damaged parts of cells are broken down and reused, keeping the system efficient and healthy.

Reduces harmful overgrowth:

Overactive mTOR has been linked to diseases such as cancer, cardiovascular disease, and neurodegenerative conditions like Alzheimer’s. By dialing back excessive growth signals, Rapamycin helps prevent these issues.

Supports stress resilience:

When cells are less focused on growing, they’re better equipped to handle stress, repair damage, and maintain long-term health.