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Ferritin

Lactic Acid

RBC Magnesium

Homocysteine

LDL Particle Number

MCHC (Mean Corpuscular Hemoglobin Concentration)

Cystatin C

Lymphocytes (Absolute)

Neutrophils (Absolute)

Free T3 (Triiodothyronine)

Ceruloplasmin

Sodium

MCV (Mean Corpuscular Volume)

Monocytes (Absolute)

Hemoglobin A1C

NRBC (Nucleated Red Blood Cells)

DHA (Docosahexaenoic Acid)

Fasting Insulin

AST (Aspartate Aminotransferase)

Uric Acid

Bicarbonate

Calcium

Free Testosterone

HS-CRP (High-Sensitivity C-Reactive Protein)

Free T4 (Thyroxine)

Creatinine

Apolipoprotein A1

DHEA-S (Dehydroepiandrosterone Sulfate)

Total Cholesterol

TPO Ab (Thyroid Peroxidase Antibodies)

Tg Ab (Thyroglobulin Antibodies)

Iron Saturation

Bilirubin (Total and Direct)

HOMA-IR (Homeostatic Model Assessment of Insulin Resistance)

Chloride

GGT (Gamma-Glutamyl Transferase)

Albumin

Sed Rate (Erythrocyte Sedimentation Rate)

Serum Iron

Copper Serum
Discover the key role IGF-1 plays as a biomarker for longevity. Understand its impact on aging and how it can be used for personalized health strategies.

IGF-1 (Insulin-Like Growth Factor 1)

IGF-1, a key biomarker for longevity, plays a crucial role in the regulation of cellular growth and proliferation. As a potent stimulator of cell growth, IGF-1 levels have a significant impact on the aging process. Elevated levels of IGF-1 have been associated with increased risk of age-related diseases, while lower levels have been linked to extended lifespan and improved healthspan. Monitoring and regulating IGF-1 levels through lifestyle interventions, such as diet and exercise, have shown promise in promoting longevity and healthy aging. Additionally, IGF-1 levels can serve as a valuable biomarker to assess the effectiveness of anti-aging interventions and to guide personalized longevity strategies.

Biomarker Explained

As a longevity expert, IGF-1 is a key biomarker for assessing an individual’s potential for healthy aging and longevity. Elevated levels of IGF-1 have been associated with an increased risk of age-related diseases, while lower levels have been linked to extended lifespan and improved healthspan. When interpreting IGF-1 levels, it is important to consider the impact on cellular growth and proliferation. To promote longevity and healthy aging, monitoring and regulating IGF-1 levels through lifestyle interventions, such as diet and exercise, have shown promise. Furthermore, IGF-1 levels can be used as a valuable biomarker to assess the effectiveness of anti-aging interventions and to guide personalized longevity strategies. By understanding the role of IGF-1 and its impact on the aging process, individuals can take proactive steps to improve their overall health and longevity.

Keywords:

Longevity, IGF-1, Biomarker, Healthy aging, Age-related diseases, Cellular growth, Lifestyle interventions

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Prescription products require an online consultation with a physician who will determine if a prescription is appropriate. See product page for important safety information. Benefits outlined on Longevity Direct are based on 3rd party studies.

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Longevity Direct logo in color – promoting personalized longevity insights and AI-driven health optimization

Rapamycin

Metformin

GLP-1

General Longevity
Heart Health
Weight Management
Glucose Control
Cognitive Function
Diabetes Prevention
Mood Support
Energy & Fatigue
Autoimmune Support
Blood Pressure
Chronic Pain & Arthritis
Aging Skin
Men’s Aging
Women’s Aging

Longevity Library
About

get Started
Client portal

Contact

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How does Rapaymcin work?

Rapamycin slows aging by targeting the mTOR pathway, shifting the body’s focus from growth to repair. It promotes cellular recycling, reduces overgrowth linked to disease, and enhances resilience to stress.

Imagine your body as a city, bustling with activity.

Cells are the workers, and mTOR (mechanistic target of rapamycin) is the city planner, deciding where to focus resources – building new structures, cleaning up waste, or repairing old ones.

As we age, mTOR often prioritizes building (cell growth) over maintenance (cellular repair), leading to “clutter” in our bodies that contributes to aging and disease.

This is where Rapamycin comes in.

It acts like a wise advisor to mTOR, convincing it to slow down unnecessary growth projects and focus on clean up and repair instead.

Specifically, Rapamycin:

Activates cellular recycling (autophagy):

Think of autophagy as the city’s waste management system. Damaged parts of cells are broken down and reused, keeping the system efficient and healthy.

Reduces harmful overgrowth:

Overactive mTOR has been linked to diseases such as cancer, cardiovascular disease, and neurodegenerative conditions like Alzheimer’s. By dialing back excessive growth signals, Rapamycin helps prevent these issues.

Supports stress resilience:

When cells are less focused on growing, they’re better equipped to handle stress, repair damage, and maintain long-term health.