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Hemoglobin A1C

25(OH)D (25-Hydroxyvitamin D)

NRBC (Nucleated Red Blood Cells)

TIBC (Total Iron Binding Capacity)

TPO Ab (Thyroid Peroxidase Antibodies)

Apolipoprotein A1

DHA (Docosahexaenoic Acid)

Fibrinogen

ALT (Alanine Aminotransferase)

LDL Particle Number

Vitamin A (Retinol)

Apolipoprotein B

Homocysteine

Uric Acid

Glucose

Iron Saturation

LDL Cholesterol (calculated)

DHEA-S (Dehydroepiandrosterone Sulfate)

WBC (White Blood Cell Count)

Ceruloplasmin

Free T4 (Thyroxine)

MCV (Mean Corpuscular Volume)

Lactic Acid

Albumin

eGFR (Estimated Glomerular Filtration Rate)

Triglycerides

HS-CRP (High-Sensitivity C-Reactive Protein)

EPA (Eicosapentaenoic Acid)

AST (Aspartate Aminotransferase)

GGT (Gamma-Glutamyl Transferase)

HOMA-IR (Homeostatic Model Assessment of Insulin Resistance)

Basophils (Absolute)

BUN (Blood Urea Nitrogen)

ApoA/ApoB Ratio

Chloride

Immature Granulocytes

RBC (Red Blood Cell Count)

Alkaline Phosphatase (ALP)

Creatinine

Copper Serum
DHEA-S, a biomarker for longevity, reflects adrenal gland function and may have potential anti-aging effects. Learn how it can impact your lifespan.

DHEA-S (Dehydroepiandrosterone Sulfate)

DHEA-S, or Dehydroepiandrosterone Sulfate, is a biomarker commonly used in longevity research. It is a sulfated version of the hormone DHEA, which is produced by the adrenal glands. DHEA-S levels decline with age, and some studies have suggested that higher levels of DHEA-S are associated with better health and potentially longer lifespan. However, more research is needed to fully understand the role of DHEA-S in longevity. As a biomarker, DHEA-S can provide valuable insight into the aging process and may hold potential for future interventions to promote healthy aging.

Biomarker Explained

DHEA-S, or Dehydroepiandrosterone Sulfate, is a widely recognized biomarker in longevity research. This sulfated version of the hormone DHEA is primarily produced by the adrenal glands and is known to decline with age. Studies have suggested that individuals with higher levels of DHEA-S may experience better health and potentially live longer. However, it is important to note that more research is needed to fully comprehend the role of DHEA-S in longevity. As a biomarker, DHEA-S provides valuable insight into the aging process and may hold potential for future interventions aimed at promoting healthy aging. While it is essential to consider DHEA-S levels in the context of an individual’s overall health and other biomarkers, monitoring DHEA-S can be a useful tool in assessing and understanding the aging process and potential longevity.

Keywords:

DHEA-S, Dehydroepiandrosterone Sulfate, biomarker, longevity, aging process, adrenal glands, health interventions

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Longevity Direct logo in color – promoting personalized longevity insights and AI-driven health optimization

Rapamycin

Metformin

GLP-1

General Longevity
Heart Health
Weight Management
Glucose Control
Cognitive Function
Diabetes Prevention
Mood Support
Energy & Fatigue
Autoimmune Support
Blood Pressure
Chronic Pain & Arthritis
Aging Skin
Men’s Aging
Women’s Aging

Longevity Library
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How does Rapaymcin work?

Rapamycin slows aging by targeting the mTOR pathway, shifting the body’s focus from growth to repair. It promotes cellular recycling, reduces overgrowth linked to disease, and enhances resilience to stress.

Imagine your body as a city, bustling with activity.

Cells are the workers, and mTOR (mechanistic target of rapamycin) is the city planner, deciding where to focus resources – building new structures, cleaning up waste, or repairing old ones.

As we age, mTOR often prioritizes building (cell growth) over maintenance (cellular repair), leading to “clutter” in our bodies that contributes to aging and disease.

This is where Rapamycin comes in.

It acts like a wise advisor to mTOR, convincing it to slow down unnecessary growth projects and focus on clean up and repair instead.

Specifically, Rapamycin:

Activates cellular recycling (autophagy):

Think of autophagy as the city’s waste management system. Damaged parts of cells are broken down and reused, keeping the system efficient and healthy.

Reduces harmful overgrowth:

Overactive mTOR has been linked to diseases such as cancer, cardiovascular disease, and neurodegenerative conditions like Alzheimer’s. By dialing back excessive growth signals, Rapamycin helps prevent these issues.

Supports stress resilience:

When cells are less focused on growing, they’re better equipped to handle stress, repair damage, and maintain long-term health.