MCV (Mean Corpuscular Volume)

Lipoprotein(a) [Lp(a)]

Ceruloplasmin

DHEA-S (Dehydroepiandrosterone Sulfate)

Sodium

Lymphocytes (Absolute)

UIBC (Unsaturated Iron Binding Capacity)

Platelet Count

MCHC (Mean Corpuscular Hemoglobin Concentration)

25(OH)D (25-Hydroxyvitamin D)

Free Testosterone

HDL Cholesterol

Immature Granulocytes

IL-6 (Interleukin-6)

Hematocrit

AST (Aspartate Aminotransferase)

Phosphorous

TSH (Thyroid Stimulating Hormone)

GGT (Gamma-Glutamyl Transferase)

Creatinine

ANA (Antinuclear Antibody)

TNF-α (Tumor Necrosis Factor-alpha)

TPO Ab (Thyroid Peroxidase Antibodies)

Reverse T3 (rT3)

RBC (Red Blood Cell Count)

RBC Magnesium

Eosinophils (Absolute)

TIBC (Total Iron Binding Capacity)

NRBC (Nucleated Red Blood Cells)

Lactic Acid

LDL Particle Size

Insulin

HS-CRP (High-Sensitivity C-Reactive Protein)

Total Cholesterol

Hemoglobin A1C

BUN (Blood Urea Nitrogen)

LDH (Lactate Dehydrogenase)

Bilirubin (Total and Direct)

Potassium

BUN/Creatinine Ratio

Discover the significance of GGT, a biomarker used in longevity research, and its potential role in predicting healthspan and lifespan.

GGT (Gamma-Glutamyl Transferase)

Gamma-Glutamyl Transferase (GGT) is a biomarker that plays a crucial role in assessing longevity and overall health. It is primarily found in the liver and helps to metabolize glutathione, an essential antioxidant that protects cells from damage. Elevated levels of GGT in the blood are often associated with liver disease, alcohol consumption, and other health issues, making it a valuable indicator of potential health risks. Additionally, GGT levels have been linked to cardiovascular disease and mortality, making it a significant biomarker for longevity assessment. Regular monitoring of GGT levels can provide important insights into an individual’s health and potential lifespan.

Biomarker Explained

Gamma-Glutamyl Transferase (GGT) is a biomarker that holds significant importance in the assessment of longevity and overall health. This enzyme, primarily present in the liver, plays a crucial role in the metabolism of glutathione, an essential antioxidant responsible for safeguarding cells against damage. Elevated levels of GGT in the bloodstream are commonly associated with liver disease, excessive alcohol consumption, and other health concerns, making it a valuable indicator of potential health risks. In addition, research has established a correlation between GGT levels and cardiovascular disease and mortality, rendering it a significant biomarker for longevity evaluation. Regular monitoring of GGT levels can provide crucial insights into an individual’s health status and potential lifespan. Therefore, interpreting GGT levels in the blood can offer valuable information regarding an individual’s overall health, potential health risks, and their expected longevity.

Keywords:

GGT, Gamma-Glutamyl Transferase, longevity, biomarker, liver disease, cardiovascular disease, antioxidant

How does Rapaymcin work?

Rapamycin slows aging by targeting the mTOR pathway, shifting the body’s focus from growth to repair. It promotes cellular recycling, reduces overgrowth linked to disease, and enhances resilience to stress.

Imagine your body as a city, bustling with activity.

Cells are the workers, and mTOR (mechanistic target of rapamycin) is the city planner, deciding where to focus resources – building new structures, cleaning up waste, or repairing old ones.

As we age, mTOR often prioritizes building (cell growth) over maintenance (cellular repair), leading to “clutter” in our bodies that contributes to aging and disease.

This is where Rapamycin comes in.

It acts like a wise advisor to mTOR, convincing it to slow down unnecessary growth projects and focus on clean up and repair instead.

Specifically, Rapamycin:

Activates cellular recycling (autophagy):

Think of autophagy as the city’s waste management system. Damaged parts of cells are broken down and reused, keeping the system efficient and healthy.

Reduces harmful overgrowth:

Overactive mTOR has been linked to diseases such as cancer, cardiovascular disease, and neurodegenerative conditions like Alzheimer’s. By dialing back excessive growth signals, Rapamycin helps prevent these issues.

Supports stress resilience:

When cells are less focused on growing, they’re better equipped to handle stress, repair damage, and maintain long-term health.