TNF-α, also known as Tumor Necrosis Factor-alpha, is a biomarker that has been extensively studied in the context of longevity. Elevated levels of TNF-α have been associated with chronic inflammation, which is a major contributor to the aging process and age-related diseases. As a result, monitoring TNF-α levels can provide valuable insight into an individual’s overall health and potential lifespan. By understanding the role of TNF-α in aging and disease, researchers and healthcare providers can develop targeted interventions to mitigate its effects, ultimately leading to improved longevity and quality of life for individuals.