Longevity Direct logo in color – promoting personalized longevity insights and AI-driven health optimization
get Started

Immature Granulocytes

ALT (Alanine Aminotransferase)

RBC Magnesium

Free T4 (Thyroxine)

ANA (Antinuclear Antibody)

Bicarbonate

Total Cholesterol

Neutrophils (Absolute)

Bilirubin (Total and Direct)

Hematocrit

Fibrinogen

GGT (Gamma-Glutamyl Transferase)

Ferritin

A/G Ratio (Albumin/Globulin Ratio)

Apolipoprotein A1

Copper Serum

BUN (Blood Urea Nitrogen)

EPA (Eicosapentaenoic Acid)

DHEA-S (Dehydroepiandrosterone Sulfate)

TNF-α (Tumor Necrosis Factor-alpha)

Reverse T3 (rT3)

Alkaline Phosphatase (ALP)

WBC (White Blood Cell Count)

AST (Aspartate Aminotransferase)

MCH (Mean Corpuscular Hemoglobin)

TPO Ab (Thyroid Peroxidase Antibodies)

Lipoprotein(a) [Lp(a)]

Lactic Acid

Free T3 (Triiodothyronine)

IL-6 (Interleukin-6)

Phosphorous

Triglycerides

TIBC (Total Iron Binding Capacity)

Platelet Count

TSH (Thyroid Stimulating Hormone)

Total Testosterone

NRBC (Nucleated Red Blood Cells)

Hemoglobin A1C

Uric Acid

Chloride
DHEA-S, a biomarker for longevity, reflects adrenal gland function and may have potential anti-aging effects. Learn how it can impact your lifespan.

DHEA-S (Dehydroepiandrosterone Sulfate)

DHEA-S, or Dehydroepiandrosterone Sulfate, is a biomarker commonly used in longevity research. It is a sulfated version of the hormone DHEA, which is produced by the adrenal glands. DHEA-S levels decline with age, and some studies have suggested that higher levels of DHEA-S are associated with better health and potentially longer lifespan. However, more research is needed to fully understand the role of DHEA-S in longevity. As a biomarker, DHEA-S can provide valuable insight into the aging process and may hold potential for future interventions to promote healthy aging.

Biomarker Explained

DHEA-S, or Dehydroepiandrosterone Sulfate, is a widely recognized biomarker in longevity research. This sulfated version of the hormone DHEA is primarily produced by the adrenal glands and is known to decline with age. Studies have suggested that individuals with higher levels of DHEA-S may experience better health and potentially live longer. However, it is important to note that more research is needed to fully comprehend the role of DHEA-S in longevity. As a biomarker, DHEA-S provides valuable insight into the aging process and may hold potential for future interventions aimed at promoting healthy aging. While it is essential to consider DHEA-S levels in the context of an individual’s overall health and other biomarkers, monitoring DHEA-S can be a useful tool in assessing and understanding the aging process and potential longevity.

Keywords:

DHEA-S, Dehydroepiandrosterone Sulfate, biomarker, longevity, aging process, adrenal glands, health interventions

Your Longevity Clinic,
from Home.

Longevity Direct is an app within Longr’s Longevity OS, a platform dedicated to extending access to longevity. 

Verify Approval for www.longevity.direct

Home

Rapamycin

Metformin

GLP-1

General Longevity
Heart Health
Weight Management
Glucose Control
Cognitive Function
Diabetes Prevention
Mood Support
Energy & Fatigue
Autoimmune Support
Blood Pressure
Chronic Pain & Arthritis
Aging Skin
Men’s Aging
Women’s Aging

Longevity Library
About

Contact

Client portal

© 2025 Longr Holdings Inc.
1007 North Orange Street | DE 19801 | U.S.A

Prescription products require an online consultation with a physician who will determine if a prescription is appropriate. See product page for important safety information. Benefits outlined on Longevity Direct are based on 3rd party studies.

Note: The above statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. If you are in need of emergency medical attention, please call 911 immediately.

Longevity Direct logo in color – promoting personalized longevity insights and AI-driven health optimization

Rapamycin

Metformin

GLP-1

General Longevity
Heart Health
Weight Management
Glucose Control
Cognitive Function
Diabetes Prevention
Mood Support
Energy & Fatigue
Autoimmune Support
Blood Pressure
Chronic Pain & Arthritis
Aging Skin
Men’s Aging
Women’s Aging

Longevity Library
About

get Started
Client portal

Contact

Questions, suggestions, reflections?

Fill out the form below and a member of our team well get back to you as soon as possible.

FAQS
Contact Form (#14)

How does Rapaymcin work?

Rapamycin slows aging by targeting the mTOR pathway, shifting the body’s focus from growth to repair. It promotes cellular recycling, reduces overgrowth linked to disease, and enhances resilience to stress.

Imagine your body as a city, bustling with activity.

Cells are the workers, and mTOR (mechanistic target of rapamycin) is the city planner, deciding where to focus resources – building new structures, cleaning up waste, or repairing old ones.

As we age, mTOR often prioritizes building (cell growth) over maintenance (cellular repair), leading to “clutter” in our bodies that contributes to aging and disease.

This is where Rapamycin comes in.

It acts like a wise advisor to mTOR, convincing it to slow down unnecessary growth projects and focus on clean up and repair instead.

Specifically, Rapamycin:

Activates cellular recycling (autophagy):

Think of autophagy as the city’s waste management system. Damaged parts of cells are broken down and reused, keeping the system efficient and healthy.

Reduces harmful overgrowth:

Overactive mTOR has been linked to diseases such as cancer, cardiovascular disease, and neurodegenerative conditions like Alzheimer’s. By dialing back excessive growth signals, Rapamycin helps prevent these issues.

Supports stress resilience:

When cells are less focused on growing, they’re better equipped to handle stress, repair damage, and maintain long-term health.