RBC (Red Blood Cell Count)

DHEA-S (Dehydroepiandrosterone Sulfate)

TNF-α (Tumor Necrosis Factor-alpha)

Glucose

Monocytes (Absolute)

TSH (Thyroid Stimulating Hormone)

Free T4 (Thyroxine)

LDL Particle Size

Chloride

LDL Particle Number

ALT (Alanine Aminotransferase)

Neutrophils (Absolute)

NRBC (Nucleated Red Blood Cells)

Free Testosterone

Free T3 (Triiodothyronine)

Bicarbonate

WBC (White Blood Cell Count)

MCH (Mean Corpuscular Hemoglobin)

Copper Serum

EPA (Eicosapentaenoic Acid)

eGFR (Estimated Glomerular Filtration Rate)

Total Protein

RDW (Red Cell Distribution Width)

Albumin

IL-6 (Interleukin-6)

Total Testosterone

Fibrinogen

TIBC (Total Iron Binding Capacity)

A/G Ratio (Albumin/Globulin Ratio)

Hemoglobin

Phosphorous

Platelet Count

Iron Saturation

MCV (Mean Corpuscular Volume)

Vitamin A (Retinol)

Tg Ab (Thyroglobulin Antibodies)

TPO Ab (Thyroid Peroxidase Antibodies)

LDH (Lactate Dehydrogenase)

IGF-1 (Insulin-Like Growth Factor 1)

Bilirubin (Total and Direct)

Discover the significance of BUN/Creatinine Ratio as a potential biomarker for assessing longevity and overall health. Learn more about its implications.

BUN/Creatinine Ratio

BUN/Creatinine Ratio is a biomarker that is often used in longevity research to assess kidney function and overall health. The ratio of blood urea nitrogen (BUN) to creatinine levels can provide valuable insights into the body’s ability to eliminate waste products and maintain proper hydration. An elevated BUN/Creatinine Ratio may indicate potential kidney dysfunction or dehydration, which can have implications for long-term health and longevity. By monitoring and optimizing this biomarker, individuals can take proactive steps to support their kidney health and overall well-being as they age.

Biomarker Explained

The BUN/Creatinine Ratio is a valuable biomarker used in longevity research to assess kidney function and overall health. This ratio is calculated by dividing the blood urea nitrogen (BUN) levels by the creatinine levels. A higher BUN/Creatinine Ratio may indicate potential kidney dysfunction or dehydration. The kidneys play a crucial role in filtering waste products from the blood and maintaining proper hydration. Therefore, an elevated ratio suggests that the body may not be effectively eliminating waste products or may be experiencing insufficient fluid intake. For individuals focused on optimizing their longevity, it is important to monitor and optimize this biomarker. Regular testing of the BUN/Creatinine Ratio can provide valuable insights into kidney health and overall well-being. By identifying and addressing potential issues early on, individuals can take proactive steps to support their kidney function and overall health as they age. In conclusion, the BUN/Creatinine Ratio is an important biomarker that provides valuable information about kidney function and hydration levels. By understanding and interpreting this ratio, individuals can take proactive measures to support their longevity and overall well-being.

Keywords:

BUN, Creatinine, Ratio, Biomarker, Longevity, Kidney function, Dehydration

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How does Rapaymcin work?

Rapamycin slows aging by targeting the mTOR pathway, shifting the body’s focus from growth to repair. It promotes cellular recycling, reduces overgrowth linked to disease, and enhances resilience to stress.

Imagine your body as a city, bustling with activity.

Cells are the workers, and mTOR (mechanistic target of rapamycin) is the city planner, deciding where to focus resources – building new structures, cleaning up waste, or repairing old ones.

As we age, mTOR often prioritizes building (cell growth) over maintenance (cellular repair), leading to “clutter” in our bodies that contributes to aging and disease.

This is where Rapamycin comes in.

It acts like a wise advisor to mTOR, convincing it to slow down unnecessary growth projects and focus on clean up and repair instead.

Specifically, Rapamycin:

Activates cellular recycling (autophagy):

Think of autophagy as the city’s waste management system. Damaged parts of cells are broken down and reused, keeping the system efficient and healthy.

Reduces harmful overgrowth:

Overactive mTOR has been linked to diseases such as cancer, cardiovascular disease, and neurodegenerative conditions like Alzheimer’s. By dialing back excessive growth signals, Rapamycin helps prevent these issues.

Supports stress resilience:

When cells are less focused on growing, they’re better equipped to handle stress, repair damage, and maintain long-term health.